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Rabbit polyclonal antibody to mouse elF2c (Ago2) protein (845-860): Affinity purified

ArtNr R-1556-100
Hersteller Biosensis
Menge 100ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IP, IHC
Specific against Mouse (Murine, Mus musculus)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products Eif2c2, Ago2, Protein argonaute-2, Protein argonaute-1, Protein argonaute-3, Argonaute1, Argonaute2, Argonaute3, mAgo1, mAgo2, Eukaryotic translation initiation factor 2C, eIF-2C 2, eIF-2C 1, eIF2C 2, Piwi/argonaute family protein meIF2C2 Protein slicer, Ago1
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Sub category
Cell Cycle Regulators-DNA Damage & Repair
products_extra_fields_value
The elF2c (Argonaute, Ago) protein is a core protein of the RNA-induced silencing complex (RISC).
products_quantity
200
storage
At least 12 months after purchase at 2 - 4AC (lyophilized formulations). After reconstitution, aliquot and store at -20AC for a higher stability and at 4AC with an appropriate antibacterial agent. Avoid freeze-thaw cycles.
formulation
Lyophilised from PBS
immunogen
A synthetic peptide corresponding to a sequence (845-860 aa) from the C-terminus of mouse elF2C conjugated to KLH.
crossreactivity
Human, mouse, rat, The Ago proteins are highly conserved so cross-reactivity with other species is expected.
conality
Rabbit
specificity
Specificity has been confirmed by IHC, WB and IP in mouse brain. This antibody is expected to recognise at least elF2c-1, 2 and 3 since they have identical C-termini.
reconstitution
Reconstitute in 100 Aul of sterile water. Centrifuge to remove any insoluble material.
specificreferences
Huang KL, Chadee AB, Chen CY, Zhang Y, Shyu AB. (2013)"Phosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fate." RNA. 2013 Jan 22. [Epub ahead of print].
Lugli G. et al (2008) Expression of microRNAs and their precursors in synaptic fractions of adult mouse forebrain. J Neurochem. Jul, 106(2):650-61.
Lugli G. et al (2005) Dicer and eIF2c are enriched at postsynaptic densities in adult mouse brain and are modified by neuronal activity in a calpain-dependent manner. J Neurochem. Aug, 94(4):896-905.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100ul
Lieferbar: In stock
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