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Rabbit polyclonal antibody to mouse elF2c (Ago2) protein (845-860): Affinity purified

Rabbit polyclonal antibody to mouse elF2c (Ago2) protein (845-860): Affinity purified

Item no.	R-1556-100
Manufacturer	Biosensis
Amount	100ul
Category	Neuroscience Metabolism Diabetes Glucose Homeostasis Molecular Targets for Neuroscience Antibodies Immunohistochemistry Immunoprecipitation Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IP, IHC
Specific against	Mouse (Murine, Mus musculus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	Eif2c2, Ago2, Protein argonaute-2, Protein argonaute-1, Protein argonaute-3, Argonaute1, Argonaute2, Argonaute3, mAgo1, mAgo2, Eukaryotic translation initiation factor 2C, eIF-2C 2, eIF-2C 1, eIF2C 2, Piwi/argonaute family protein meIF2C2 Protein slicer, Ago1
Available
Sub category	Cell Cycle Regulators-DNA Damage & Repair
products_extra_fields_value	The elF2c (Argonaute, Ago) protein is a core protein of the RNA-induced silencing complex (RISC).
products_quantity	200
storage	At least 12 months after purchase at 2 - 4AC (lyophilized formulations). After reconstitution, aliquot and store at -20AC for a higher stability and at 4AC with an appropriate antibacterial agent. Avoid freeze-thaw cycles.
formulation	Lyophilised from PBS
immunogen	A synthetic peptide corresponding to a sequence (845-860 aa) from the C-terminus of mouse elF2C conjugated to KLH.
crossreactivity	Human, mouse, rat, The Ago proteins are highly conserved so cross-reactivity with other species is expected.
conality	Rabbit
specificity	Specificity has been confirmed by IHC, WB and IP in mouse brain. This antibody is expected to recognise at least elF2c-1, 2 and 3 since they have identical C-termini.
reconstitution	Reconstitute in 100 Aul of sterile water. Centrifuge to remove any insoluble material.
specificreferences	Huang KL, Chadee AB, Chen CY, Zhang Y, Shyu AB. (2013)"Phosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fate." RNA. 2013 Jan 22. [Epub ahead of print]. Lugli G. et al (2008) Expression of microRNAs and their precursors in synaptic fractions of adult mouse forebrain. J Neurochem. Jul, 106(2):650-61. Lugli G. et al (2005) Dicer and eIF2c are enriched at postsynaptic densities in adult mouse brain and are modified by neuronal activity in a calpain-dependent manner. J Neurochem. Aug, 94(4):896-905.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 10/16/2025

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