Vergleich

Chicken polyclonal antibody to Neurofilament Medium

ArtNr C-1393-50
Hersteller Biosensis
Menge 50ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, ICC
Specific against other
Host Chicken
Isotype IgY
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products NF-M, Nefm, Nef3, Nfm, Neurofilament medium polypeptide, 160 kDa neurofilament protein, Neurofilament 3, Neurofilament triplet M protein
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Sub category
Development-Cell Markers
products_extra_fields_value
Neurofilaments are composed of three intermediate filament proteins: light (ca.68 kDa), medium (ca.160 kDa) and heavy (ca.200 kDa), which are involved in the maintenance of the neuronal caliber. Neurofilament medium runs on SDS-PAGE gels in the range 145-170 kDa, with some variation in different species.
products_quantity
200
storage
After reconstitution of lyophilised antibody, aliquot and store at -20AC for a higher stability. Avoid freeze-thaw cycles.
formulation
Lyophilised with 5% trehalose
immunogen
Recombinant fusion protein containing the extreme C-terminal segment of rat NF-M.
crossreactivity
Hu, Rat, Ms, Fel, Chk. Predicted to react with other mammalian tissues due to sequence homology.
conality
Chicken
specificity
Specifically recognizes the medium neurofilament subunit NF-L in WB. Band appears at ca.145 kDa in WB from rodent and ca.160 kDa for human and bovine WB.
reconstitution
Reconstitute in sterile distilled water. Centrifuge to remove any insoluble material.
specificreferences
1. Jarjour A.A. et al (2007) Maintenance of axo-oligodendroglial paranodal junctions requires DCC and netrin-1. J Neurosci. 2008 Oct 22, 28(43):11003-14.
2. Rangaraju S. et al (2009) Molecular architecture of myelinated peripheral nerves is supported by calorie restriction with aging. Aging Cell. 2009 Apr, 8(2):178-91.
3. Pearse D.D. et al (2007) Transplantation of Schwann cells and/or olfactory ensheathing glia into the contused spinal cord: Survival, migration, axon association, and functional recovery. Glia. 2007 Jul, 55(9):976-1000.
4. Shaw G. et al (2004) Characterization of the bovine neurofilament NF-M protein and cDNA sequence, and identification of in vitro and in vivo calpain cleavage sites. Biochem Biophys Res Commun. 2004 Dec 10, 325(2):619-25.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50ul
Lieferbar: In stock
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