Vergleich

Native Human Serum Aminopeptidase N (ANPEP) Europäischer Partner

ArtNr BTZ-30801003
Hersteller BioTeZ
Menge 200 ug/1 ml
Kategorie
Typ Proteins Native
Format Liquid
Specific against Human (Homo sapiens)
Protein Familie Aminopeptidase
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Lieferbar
Purity
>90%
Product Subcategory
EC 3.4.11.2
Pathway and Disease
Diseases associated with ANPEP include Tetrasomy 21 and Acute Leukemia. Among its related pathways are Hematopoietic cell lineage and Transport to the Golgi and subsequent modification
Description
ANPEP plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. May play a critical role in the pathogenesis of cholesterol gallstone disease. May be involved in the metabolism of regulatory peptides of diverse cell types, responsible for the processing of peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. Found to cleave antigen peptides bound to major histocompatibility complex class II molecules of presenting cells and to degrade neurotransmitters at synaptic junctions. Is also implicated as a regulator of IL-8 bioavailability in the endometrium, and therefore may contribute to the regulation of angiogenesis. Is used as a marker for acute myeloid leukemia and plays a role in tumor invasion. In case of human coronavirus 229E (HCoV-229E) infection, serves as receptor for HCoV-229E spike glycoprotein. Mediates as well human cytomegalovirus (HCMV) infection.
Applications Info
Screening of inhibitors, Characterization of structure and function, Target for angiogenesis
Alternate Names
ANPEP; Myeloid Plasma Membrane Glycoprotein CD13, Membrane Alanyl Aminopeptidase
Sequence
MAKGFYISKSLGILGILLGVAAVCTIIALSVVYSQ EKNKNANSSPVASTTPSASATTNPASATTLDQSKA WNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKG SSTVRFTCKEATDVIIIHSKKLNYTLSQGHRVVLR GVGGSQPPDIDKTELVEPTEYLVVHLKGSLVKDSQ YEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATT QMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTA LSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLL AFIVSEFDYVEKQASNGVLI RIWARPSAIAAGHG DYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDF NAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVT VIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEY LGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHP LSTPASEINTPAQISELFDAISYSKGASVLRMLSS FLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEA VNNRSIQLPTTVRDIMNRWTLQMGFPVITVDTSTG TLSQEHFLLDPDSNVTRPSEFNYVWIVPITSIRDG RQQQDY WLIDVRAQNDLFSTSGNEWVLLNLNVTG YYRVNYDEENWRKIQTQLQRDHSAIPVINRAQIIN DAFNLASAHKVPVTLALNNTLFLIEERQYMPWEAA LSSLSYFKLMFDRSEVYGPMKNYLKKQVTPLFIHF RNNTNNWREIPENLMDQYSEVNAISTACSNGVPEC EEMVSGLFKQWMENPNNNPIHPNLRSTVYCNAIAQ GGEEEWDFAWEQFRNATLVNEADKLRAALACSKEL WILNRYLSYTLNPDLIRKQDATSTIISITNNVIGQ GLVWDFVQSNWKKLFNDYGGGSFSFSN LIQAVTR RFSTEYELQQLEQFKKDNEETGFGSGTRALEQALE KTKANIKWVKENKEVVLQWFTENSK
Accession No
P15144
Composition
20 mM Tris-HCl, pH 7.4, 500 mM NaCl, 1mM CaCl2
Storage
Store at -70C
Target Modification
Yes
Expression System
Human Serum
Product Subtype
full length
Active?
Yes
Tag
untagged
Gene ID
290
Molecular Weight
110-130 kDa
Shipping Temp Min
dry ice
Product description long
Aminopeptidase N is prepared from human serum certified to be negative for HBsAg and for antibodies to HIV and HCV.
Purification
Mentioned in the data sheet
Restrictions
For Research Use only.
NCBI Official Symbol
ANPEP

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 ug/1 ml
Lieferbar: In stock
lieferbar

Vergleichen

Auf den Wunschzettel

Angebot anfordern

Lieferzeit anfragen

Technische Frage stellen

Bulk-Anfrage stellen

Fragen zum Produkt?
 
Schließen