Coelenterazine, 2-methyl derivative (Methyl coelenterazine)

Enzyme Substrates>Luciferase Substrates

Methyl coelenterazine (Coelenterazine, 2-methyl analog) has been reported to be a superior antioxidant for cells against reactive oxygen species (ROS) such as singlet oxygen and superoxide anion. The coelenterazine derivative is membrane-permeant, nontoxic and highly reactive toward ROS. As oxidative stress is believed to be a mediator of apoptosis, methyl coelenterazine should be another important tool for studies of apoptosis.Coelenterazine products have been used to detect superoxide and peroxynitrite via chemiluminescence.

• Yellow solid soluble in MeOH or EtOH
• Store at -20° C and protect from light
• C₂₀H₁₇N₃O₂
• MW: 331.37

Store with desiccant; Protect from light

Stable; Color should be yellow, may contain dark red or brown flecks. If uniformly brown, it is oxidized and needs to be replaced.

Chemistry reagents or solutions