Hersteller |
Bioworld Technology, Inc
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Human, Mouse, Rat |
Applikationen |
WB, IF, IP, IHC, ICC |
Menge |
50ul |
Host |
Rabbit |
ArtNr |
BS6572-50 |
Targets |
CTNND1 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Swiss-Prot |
O60716 |
Application all |
WB: 1:500ca.1:2000 IHC: 1:50ca.1:200 ICC/IF: 1:50ca.1:200 IP: 1:50ca.1:200 |
Background |
The alpha, beta, delta, and gamma -catenins are proteins that bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. delta-catenin interacts with Presenilin 1 and is expressed in the brain. The gene encoding delta-catenin maps to human chromosome 5p15.2. A hemizygous loss of the gene encoding delta-catenin leads to the mental retardation associated with Cri-du-Chat syndrome. gamma-catenin, also known as plakoglobin, is an 80-88 kDa protein that binds alpha-catenin and N-cadherin. In addition, the transmembrane phosphatase PTPm associates with catenin/cadherin complexes and may regulate complex signaling. |
Product |
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
Catenin-delta1 pAb detects endogenous levels of Catenin-delta1 protein. |
WB |
Western blot analysis of Catenin-delta1 polyclonal antibody |
IF |
Immunofluorescence analysis of U2OS cells, using Catenin-delta1 polyclonal antibody |
BiowMW |
ca. 108 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Catenin delta1, Catenin delta-1, Cadherin-associated Src substrate, Short name=CAS, p120 catenin, p120(ctn), p120(cas), CTNND1, KIAA0384 |
Immunogen |
Recombinant full length Human Catenin-delta1. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.