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Catenin-delta1 polyclonal antibody

Catenin-delta1 polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Molecular Targets for Neuroscience Neural Signaling Protein Aggregation, Clearance & Misfolding Neural Adhesion Molecules Antibodies Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Mouse, Rat
Applications	WB, IF, IP, IHC, ICC
Amount	50ul
Host	Rabbit
Item no.	BS6572-50
Targets	CTNND1
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	O60716
Application all	WB: 1:500ca.1:2000 IHC: 1:50ca.1:200 ICC/IF: 1:50ca.1:200 IP: 1:50ca.1:200
Background	The alpha, beta, delta, and gamma -catenins are proteins that bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. delta-catenin interacts with Presenilin 1 and is expressed in the brain. The gene encoding delta-catenin maps to human chromosome 5p15.2. A hemizygous loss of the gene encoding delta-catenin leads to the mental retardation associated with Cri-du-Chat syndrome. gamma-catenin, also known as plakoglobin, is an 80-88 kDa protein that binds alpha-catenin and N-cadherin. In addition, the transmembrane phosphatase PTPm associates with catenin/cadherin complexes and may regulate complex signaling.
Product	1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	Catenin-delta1 pAb detects endogenous levels of Catenin-delta1 protein.
WB	Western blot analysis of Catenin-delta1 polyclonal antibody
IF	Immunofluorescence analysis of U2OS cells, using Catenin-delta1 polyclonal antibody
BiowMW	ca. 108 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	Catenin delta1, Catenin delta-1, Cadherin-associated Src substrate, Short name=CAS, p120 catenin, p120(ctn), p120(cas), CTNND1, KIAA0384
Immunogen	Recombinant full length Human Catenin-delta1.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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