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Anti-Angiogenin ANG Antibody

Anti-Angiogenin ANG Antibody

ArtNr	BOS-A00146-2
Hersteller	Boster
Menge	100 ul
Quantity options	0.1 mg 100 ul
Kategorie	Neuroscience Neural Signaling Immunohistochemistry Western Blot ELISA Immunofluorescence Immunostaining
Format	Liquid
Applikationen	IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Alias	Angiogenin,3.1.27.-,Ribonuclease 5,RNase 5,ANG,RNASE5
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	16550 MW
Clonality	Polyclonal
Application Details	IHC: 1:50-1:200
Gene Name	ANG
Gene Full Name	Angiogenin
Immunogen	A synthetic peptide corresponding to residues in Human ANG
Contents	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Concentration	1 mg/ml
Protein Name	Angiogenin
Protein Function	Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo.
Subcellular Localization	Cytoplasmic vesicle, secretory vesicle lumen
Description	Boster Bio Anti-Angiogenin ANG Antibody catalog # A00146-2. Tested in IHC applications. This antibody reacts with Human, Mouse.
Tissue Specificity	Expressed predominantly in the liver. Also detected in endothelial cells and spinal cord neurons.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-A00146-2-datasheet.pdf

BOS-A00146-2-safety-datasheet.pdf