Anti-ABCG2 Antibody

Primary Antibodies

72314 MW

WB: 1:1, 000-1:2, 000
ICC: 1:50-1:200
IHC: 1:50-1:200
FC: 1:50-1:100

ATP-binding cassette sub-family G member 2

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

1 mg/ml

High-capacity urate exporter functioning in both renal
and extrarenal urate excretion. Plays a role in porphyrin
homeostasis as it is able to mediates the export of protoporhyrin
IX (PPIX) both from mitochondria to cytosol and from cytosol to
extracellular space, and cellular export of hemin, and heme.
Xenobiotic transporter that may play an important role in the
exclusion of xenobiotics from the brain. Appears to play a major
role in the multidrug resistance phenotype of several cancer cell
lines. Implicated in the efflux of numerous drugs and xenobiotics:
mitoxantrone, the photosensitizer pheophorbide, camptothecin,
methotrexate, azidothymidine (AZT), and the anthracyclines
daunorubicin and doxorubicin.

Boster Bio Anti-ABCG2 Antibody catalog # A00457-1. Tested in WB, ICC/IF, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse.