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Anti-ABCG2 Antibody

Anti-ABCG2 Antibody

Item no.	BOS-A00457-1
Manufacturer	Boster
Amount	100 ul
Category	Oncology Food Safety Allergenes Neuroscience Neural Lineage Markers Neuroinflammation Antibodies Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies By Organ Breast Cancer Immunochemistry
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, FC, IF, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ATP-binding cassette sub-family G member 2,Breast cancer resistance protein,CDw338,Mitoxantrone resistance-associated protein,Placenta-specific ATP-binding cassette transporter,Urate exporter,CD338,ABCG2,ABCP,BCRP,BCRP1,MXR
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	72314 MW
Clonality	Polyclonal
Application Details	WB: 1:1, 000-1:2, 000 ICC: 1:50-1:200 IHC: 1:50-1:200 FC: 1:50-1:100
Gene Name	ABCG2
Gene Full Name	ATP-binding cassette sub-family G member 2
Immunogen	recombinant protein
Contents	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification	ProA affinity purified
Concentration	1 mg/ml
Protein Name	ATP-binding cassette sub-family G member 2
Protein Function	High-capacity urate exporter functioning in both renal and extrarenal urate excretion. Plays a role in porphyrin homeostasis as it is able to mediates the export of protoporhyrin IX (PPIX) both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. Implicated in the efflux of numerous drugs and xenobiotics: mitoxantrone, the photosensitizer pheophorbide, camptothecin, methotrexate, azidothymidine (AZT), and the anthracyclines daunorubicin and doxorubicin.
Subcellular Localization	Cell membrane
Description	Boster Bio Anti-ABCG2 Antibody catalog # A00457-1. Tested in WB, ICC/IF, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse.
Tissue Specificity	Highly expressed in placenta. Low expression in small intestine, liver and colon.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A00457-1-datasheet.pdf

BOS-A00457-1-safety-datasheet.pdf