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Anti-Nestin Antibody (S1409)

Anti-Nestin Antibody (S1409)

ArtNr	BOS-A00806-1-80ul
Hersteller	Boster
Menge	80 ul
Quantity options	400 ul 80 ul
Kategorie	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Development Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Neurodegeneration Markers Progenitor Markers
Applikationen	WB, FC, IF, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Alias	Nestin,NES
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight	177439 Da
Clonality	Polyclonal
Application Details	IF: 1:25 WB: 1:2000 IHC-P: 1:25 FC: 1:25
Gene Name	NES
Background	Nestin is a class VI intermediate filament protein expressed predominantly in stem cells of the neural tube but absent from virtually all differentiated CNS cells. In the CNS, nestin is downregulated upon differentiation and replaced by neurofilaments. Transient expression of nestin has been postulated as a key step committing cells to the neural differentiation pathway. Nestin expression has also been observed in pancreatic hematopoietic stem cell populations.
Immunogen	This Nestin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1389-1416 amino acids from human Nestin.
Contents	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Manufacturer - Research Category	Cancer, Cardiovascular, Developmental Biology, Neuroscience, Signal Transduction
Protein Function	Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen- stimulated proliferation of neural progenitor cells (By similarity).
Description	Boster Bio Anti-Nestin Antibody (S1409) (Catalog # A00806-1). Tested in WB, IHC-P, IF, Flow Cytometry application(s). This antibody reacts with Human.
Tissue Specificity	CNS stem cells.

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BOS-A00806-1-80ul-datasheet.pdf

BOS-A00806-1-80ul-safety-datasheet.pdf