Anti-ADP-ribosylation factor 6 ARF6 Antibody

Primary Antibodies

20082 MW

ARF6 antibody can be used for detection of ARF6 by Western blot at 1 - 2 ?g/ml. Antibody can also be used for Immunohistochemistry starting at 5 ?g/mL. For immunofluorescence start at 20 ?g/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

ADP-ribosylation factor 6

ARF6 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human ARF6. The immunogen is located within the last 50 amino acids of ARF6.

ARF6 antibody is affinity chromatography purified via peptide column.

Signal Transduction

GTP-binding protein involved in protein trafficking that
regulates endocytic recycling and cytoskeleton remodeling
(PubMed:11266366, PubMed:21170023, PubMed:16737952,
PubMed:7589240, PubMed:18400762). Required for normal completion
of mitotic cytokinesis (By similarity). Plays a role in the
reorganization of the actin cytoskeleton and the formation of
stress fibers (By similarity). Involved in the regulation of
dendritic spine development, contributing to the regulation of
dendritic branching and filopodia extension (PubMed:14978216).
Plays an important role in membrane trafficking, during junctional
remodeling and epithelial polarization. Regulates surface levels
of adherens junction proteins such as CDH1 (By similarity).
Required for NTRK1 sorting to the recycling pathway from early
endosomes (By similarity).

Boster Bio Anti-ADP-ribosylation factor 6 ARF6 Antibody (Catalog # A00927). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Ubiquitous, with higher levels in heart,
substantia nigra, and kidney.