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Anti-NAT1 Antibody Picoband® Europäischer Partner

ArtNr BOS-A01386-1-Fluoro594
Hersteller Boster
Menge 100 ug/vial
Quantity options 100 ug/vial 10 ug 100 ug/vial 100 ug/vial 100 ug/vial 100 ug 100 ug 100 ug 100 ug/vial 100 ug/vial 100 ug/vial 100 ug/vial
Typ Antibody Polyclonal
Format Lyophilized
Applikationen FC
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations 1. Entrez Gene: N-acetyltransferase 1 (arylamine N-acetyltransferase).
2. De León, J. H.; Vatsis, K. P.; Weber, W. W. (2000). Characterization of naturally occurring and recombinant human N-acetyltransferase variants encoded by NAT1. Molecular Pharmacology. 58 (2): 288–299.
3. Gubin, A. N.; Njoroge, J. M.; Bouffard, G. G.; Miller, J. L. (1999). Gene Expression in Proliferating Human Erythroid Cells. Genomics. 59(2): 168–177.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Arylamine N-acetyltransferase 1,2.3.1.5,Arylamide acetylase 1,Monomorphic arylamine N-acetyltransferase,MNAT,N-acetyltransferase type 1,NAT-1,NAT1,AAC1,
Lieferbar
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Calculated Molecular weight
33899 MW
Clonality
Polyclonal
Gene Name
NAT1
Gene Full Name
Arylamine N-acetyltransferase 1
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
N-acetyltransferase 1 (arylamine N-acetyltransferase) is a protein that in humans is encoded by the NAT1 gene. This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human NAT1, different from the related mouse sequence by six amino acids, and from the related rat sequence by five amino acids.
Contents
Each vial contains 50% glycerol,  0.9% NaCl,  0.2% Na2HPO4,  0.02% NaN3.
Purification
Immunogen affinity purified.
Manufacturer - Research Category
Amino Acid Metabolism, Amino Acids, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction
Protein Name
Arylamine N-acetyltransferase 1
Protein Function
Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.
Subcellular Localization
Cytoplasm.
Manufacturer - Cross Reactivity
No cross-reactivity with other proteins.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
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