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Anti-MAP1LC3A Antibody Picoband® Europäischer Partner

ArtNr BOS-A01543-2-FITC
Hersteller Boster
Menge 100 ug
Quantity options 100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Kategorie
Typ Antibody
Format Lyophilized
Applikationen WB
Specific against Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag FITC
Citations 1. Entrez Gene: MAP1LC3A microtubule-associated protein 1 light chain 3 alpha.
2. Mann SS, Hammarback JA (May 1997). Gene localization and developmental expression of light chain 3: a common subunit of microtubule-associated protein 1A(MAP1A) and MAP1B. J Neurosci Res. 43 (5): 535–44.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Microtubule-associated proteins 1A/1B light chain 3A,Autophagy-related protein LC3 A,Autophagy-related ubiquitin-like modifier LC3 A,MAP1 light chain 3-like protein 1,MAP1A/MAP1B light chain 3 A,MAP1A/MAP1B LC3 A,Microtubule-associated protein 1 light chain 3 alpha,MAP1LC3A
Lieferbar
Manufacturer - Category
Primary Antibodies
Storage Conditions
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Observed Molecular weight
18 kDa
Clonality
Polyclonal
Application Details
Western blot, 0.25-0.5 μg/ml, Mouse, Rat
Gene Name
MAP1LC3A
Gene Full Name
microtubule associated protein 1 light chain 3 alpha
Background
Microtubule-associated proteins 1A/1B light chain 3A is a protein that in humans is encoded by the MAP1LC3A gene. MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human MAP1LC3A, identical to the related mouse and rat sequences.
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
Purification
Immunogen affinity purified.
Reconstitution
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category
Cancer, Cardiovascular, Cell Death, Cytoskeleton, Cytoskeleton/ECM, Metabolism, Metabolism Processes, Microtubules, Pathways and Processes, Signal Transduction
Protein Function
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) (PubMed:20713600, PubMed:24290141). Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed:20713600).
Subcellular Localization
Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Cytoplasmic vesicle, autophagosome.
Description
Boster Bio Anti-MAP1LC3A Antibody Picoband® catalog # A01543-2. Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.
Manufacturer - Alias
Microtubule-associated proteins 1A/1B light chain 3A, Autophagy-related protein LC3 A, Autophagy-related ubiquitin-like modifier LC3 A, MAP1 light chain 3-like protein 1, MAP1A/MAP1B light chain 3 A, MAP1A/MAP1B LC3 A, Microtubule-associated protein 1 light chain 3 alpha, MAP1LC3A
Manufacturer - Cross Reactivity
No cross-reactivity with other proteins.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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