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Anti-TCPTP/PTPN2 Antibody Picoband® Europäischer Partner

ArtNr BOS-A01597-1-10ug
Hersteller Boster
Menge 10 ug
Quantity options 100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Kategorie
Typ Antibody
Format Lyophilized
Applikationen WB, FC, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations 1. "Entrez Gene: PTPN2 protein tyrosine phosphatase, non-receptor type 2".
2. Brown-Shimer S, Johnson KA, Lawrence JB, Johnson C, Bruskin A, Green NR, Hill DE (Aug 1990). "Molecular cloning and chromosome mapping of the human gene encoding protein phosphotyrosyl phosphatase 1B". Proc Natl Acad Sci U S A 87 (13): 5148–52.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Multidrug resistance-associated protein 4,ATP-binding cassette sub-family C member 4,MRP/cMOAT-related ABC transporter,Multi-specific organic anion transporter B,MOAT-B,ABCC4,MRP4
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Molecular Weight
48 kDa
Calculated Molecular weight
149527 MW
Clonality
Polyclonal
Application Details
Western blot, 0.25-0.5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/ml, -
Gene Name
PTPN2
Gene Full Name
Multidrug resistance-associated protein 4
Manufacturer - Specificity
No cross-reactivity with other proteins.
Background
TCPTP is also called as PTPN2. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported.
Immunogen
E.coli-derived human TCPTP/PTPN2 recombinant protein (Position: M1-R255).
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
Purification
Immunogen affinity purified.
Reconstitution
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category
ATPases, Cancer, Channels, Drug Metabolism, Metabolism, Plasma Membrane, Signal Transduction
Protein Name
Multidrug resistance-associated protein 4
Protein Function
May be an organic anion pump relevant to cellular detoxification.
Subcellular Localization
Membrane; Multi-pass membrane protein.
Description
Boster Bio Anti-TCPTP/PTPN2 Antibody Picoband® catalog # A01597-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Widely expressed, with particularly high levels in prostate, but is barely detectable in liver.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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