Anti-SREBF2 Antibody

ArtNr	BOS-A01678-1
Hersteller	Boster
Menge	100 ul
Quantity options	0.1 mg 100 ul
Kategorie	Metabolism Diabetes Cholesterol & Lipid Metabolism Obesity Immunohistochemistry Western Blot ELISA Immunofluorescence Immunostaining Other Lipid\Cholesterol Metabolism Modulators
Format	Liquid
Applikationen	WB, IF, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Alias	Sterol regulatory element-binding protein 2,SREBP-2,Class D basic helix-loop-helix protein 2,bHLHd2,Sterol regulatory element-binding transcription factor 2,Processed sterol regulatory element-binding protein 2,SREBF2,BHLHD2,SREBP2
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	123688 MW
Clonality	Polyclonal
Application Details	WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200
Gene Name	SREBF2
Gene Full Name	Sterol regulatory element-binding protein 2
Immunogen	Recombinant protein of human SREBF2
Contents	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Concentration	1 mg/ml
Protein Name	Sterol regulatory element-binding protein 2
Protein Function	Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway (By similarity). Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes.
Subcellular Localization	Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Moves from the endoplasmic reticulum to the Golgi in the absence of sterols.
Description	Boster Bio Anti-SREBF2 Antibody catalog # A01678-1. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Ubiquitously expressed in adult and fetal tissues.

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BOS-A01678-1-datasheet.pdf

BOS-A01678-1-safety-datasheet.pdf