Anti-Integrin alpha 5/ITGA5 Antibody Picoband®

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

40895 MW

Western blot, 0.1-0.5 μg/ml
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml
ELISA, 0.1-0.5 μg/ml

integrin, alpha 5 (fibronectin receptor, alpha polypeptide)

Integrin alpha-5, also known as FNRA or VLA5A, is a protein that in humans is encoded by the ITGA5 gene. The product of this gene belongs to the integrin alpha chain family. Integrins are integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Cell Adhesion, Cytoskeleton/ECM, Integrins, Signal Transduction

Membrane; Single-pass type I membrane protein. Cell junction, focal adhesion.

Highest expression in the prostate, small intestine, colon, kidney and liver.