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Anti-OtoCadherin-23 CDH23 Antibody

Anti-OtoCadherin-23 CDH23 Antibody

ArtNr	BOS-A02149-1
Hersteller	Boster
Menge	100 ul
Quantity options	100 ul 100 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Neural Adhesion Molecules By Cell Type Carcinoma Cell Biology Cell Movement Cell Adhesion Immunohistochemistry Western Blot
Format	Liquid
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Alias	Cadherin-23
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Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	369494 MW
Clonality	Polyclonal
Application Details	WB: 1:500-1:2000 IHC: 1:50-1:200
Gene Name	CDH23
Gene Full Name	Cadherin-23
Immunogen	Recombinant full length Human CDH23.
Contents	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Concentration	1 mg/ml
Protein Name	Cadherin-23
Protein Function	Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.
Subcellular Localization	Cell membrane; Single-pass type I membrane protein.
Description	Boster Bio Anti-OtoCadherin-23 CDH23 Antibody catalog # A02149-1. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Particularly strong expression in the retina (PubMed:11138009). Found also in the cochlea.

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Arbeitsanleitung (Data Sheet) anfordern

BOS-A02149-1-datasheet.pdf

BOS-A02149-1-safety-datasheet.pdf