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Anti-BTC Antibody Picoband® Europäischer Partner

ArtNr BOS-A02171-3-carrier-free
Hersteller Boster
Menge 100 ug
Quantity options 100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Kategorie
Typ Antibody Primary
Format Lyophilized
Applikationen WB, IHC
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations 1. Elbein SC, Wang X, Karim MA, et al. (2006). Analysis of coding variants in the betacellulin gene in type 2 diabetes and insulin secretion in African American subjects. BMC Med. Genet. 7: 62.
2. Kim HS, Shin HS, Kwak HJ, Cho CH, Lee CO, Koh GY (February 2003). Betacellulin induces angiogenesis through activation of mitogen-activated protein kinase and phosphatidylinositol 3'-kinase in endothelial cell. FASEB J. 17 (2): 318–20.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Probetacellulin,Betacellulin,BTC,BTC
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Conjugate / Tag
carrier-free
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight
15 kDa
Calculated Molecular weight
63692 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5μg/ml
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml
Gene Name
BTC
Gene Full Name
betacellulin
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
Betacellulin is a protein that in humans is encoded by the BTC gene located on chromosome 4 at locus 4q13-q21. This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients.
Immunogen
E. coli-derived human BTC recombinant protein (Position: D32-Y111).
Contents
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category
Cancer, Growth Factors, Growth Factors/Hormones, Signal Transduction
Protein Name
Sentrin-specific protease 1
Protein Function
Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.
Subcellular Localization
Betacellulin: Secreted, extracellular space.
Description
Boster Bio Anti-BTC Antibody Picoband® catalog # A02171-3. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Highly expressed in testis.
Manufacturer - Cross Reactivity
No cross-reactivity with other proteins.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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