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Anti-GLUT9/SLC2A9 Antibody Picoband®

Anti-GLUT9/SLC2A9 Antibody Picoband®

ArtNr	BOS-A02245-APC
Hersteller	Boster
Menge	100 ug
Quantity options	100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Kategorie	Oncology Antibodies Flow Cytometry Immunohistochemistry Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies By Organ Lung Cancer Immunostaining Immunochemistry
Typ	Primary Antibody
Format	Lyophilized
Applikationen	WB, FC, IF, IHC, ICC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	APC
Citations	1. Chiba, T., Matsuo, H., Nagamori, S., Nakayama, A., Kawamura, Y., Shimizu, S., Sakiyama, M., Hosoyamada, M., Kawai, S., Okada, R., Hamajima, N., Kanai, Y., Shinomiya, N. Identification of a hypouricemia patient with SLC2A9 R380W, a pathogenic mutation for renal hypouricemia type 2. Nucleosides Nucleotides Nucleic Acids 33: 261-265, 2014. 2. Dinour, D., Gray, N. K., Campbell, S., Shu, X., Sawyer, L., Richardson, W., Rechavi, G., Amariglio, N., Ganon, L., Sela, B.-A., Bahat, H., Goldman, M., Weissgarten, J., Millar, M. R., Wright, A. F., Holtzman, E. J. Homozygous SLC2A9 mutations cause severe renal hypouricemia. J. Am. Soc. Nephrol. 21: 64-72, 2010. 3. Dinour, D., Gray, N. K., Ganon, L., Knox, A. J. S., Shalev, H., Sela, B.-A., Campbell, S., Sawyer, L., Shu, X., Valsamidou, E., Landau, D., Wright, A. F., Holtzman, E. J. Two novel homozygous SLC2A9 mutations cause renal hypouricemia type 2. Nephrol. Dial. Transplant. 27: 1035-1041, 2012.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Solute carrier family 2,facilitated glucose transporter member 9,Glucose transporter type 9,GLUT-9,Urate transporter,SLC2A9,GLUT9
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	59 kDa
Clonality	Polyclonal
Application Details	Western blot, 0.25-0.5μg/ml, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 2μg/ml, Human Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells, Human ELISA, 0.1-0.5μg/ml
Gene Name	SLC2A9
Gene Full Name	solute carrier family 2 (facilitated glucose transporter), member 9
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	Solute carrier family 2, facilitated glucose transporter member 9, also known as SLC2A9, is a protein that in humans is encoded by the SLC2A9 gene. This gene encodes a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. This gene is mapped to 4p16.1. The encoded protein may play a role in the development and survival of chondrocytes in cartilage matrices. This gene transports urate and fructose. It may have a role in the urate reabsorption by proximal tubules. This gene also transports glucose at low rate.
Immunogen	E.coli-derived human GLUT9/SLC2A9 recombinant protein (Position: R7-P540).
Contents	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category	Signal Transduction
Protein Name	Solute carrier family 2, facilitated glucose transporter member 9
Protein Function	Urate transporter, which may play a role in the urate reabsorption by proximal tubules. Does not transport glucose, fructose or galactose.
Subcellular Localization	Basolateral cell membrane. Multi-pass membrane protein. Plasma membrane. Apical cell membrane. Multi-pass membrane protein. Basolateral cell membrane. Multi-pass membrane protein.
Description	Boster Bio Anti-GLUT9/SLC2A9 Antibody Picoband® catalog # A02245. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Most strongly expressed in basolateral membranes of proximal renal tubular cells, liver and placenta. Also detected in lung, blood leukocytes, heart skeletal muscle and chondrocytes from articular cartilage. Isoform 2 is only detected in the apical membranes of polarized renal tubular cells and placenta. Isoform 1 and isoform 2 are detected in kidney membrane (at protein level).

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BOS-A02245-APC-datasheet.pdf

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