Anti-PLA2G2A Antibody

Primary Antibodies

16083 MW

WB: 1:500-1:2000

Phospholipase A2, membrane associated

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

1 mg/ml

Catalyzes the calcium-dependent hydrolysis of the 2-acyl
groups in 3-sn-phosphoglycerides (PubMed:2925633). Thought to
participate in the regulation of phospholipid metabolism in
biomembranes including eicosanoid biosynthesis. Independent of its
catalytic activity, acts as a ligand for integrins
(PubMed:18635536, PubMed:25398877). Binds to and activates
integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1
(PubMed:18635536, PubMed:25398877). Binds to a site (site 2) which
is distinct from the classical ligand-binding site (site 1) and
induces integrin conformational changes and enhanced ligand
binding to site 1 (PubMed:25398877). Induces cell proliferation in
an integrin-dependent manner (PubMed:18635536).

Boster Bio Anti-PLA2G2A Antibody catalog # A02259. Tested in WB applications. This antibody reacts with Human, Mouse.