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Anti-PLA2G2A Antibody

Anti-PLA2G2A Antibody

Item no.	BOS-A02259
Manufacturer	Boster
Amount	100 ul
Category	Metabolism Cholesterol & Lipid Metabolism Western Blot Enzymes Fatty Acid Catabolism
Format	Liquid
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Alias	Phospholipase A2,membrane associated,3.1.1.4
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	16083 MW
Clonality	Polyclonal
Application Details	WB: 1:500-1:2000
Gene Name	PLA2G2A
Gene Full Name	Phospholipase A2, membrane associated
Immunogen	Recombinant protein of human PLA2G2A.
Contents	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Concentration	1 mg/ml
Protein Name	Phospholipase A2, membrane associated
Protein Function	Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:2925633). Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Independent of its catalytic activity, acts as a ligand for integrins (PubMed:18635536, PubMed:25398877). Binds to and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 (PubMed:18635536, PubMed:25398877). Binds to a site (site 2) which is distinct from the classical ligand-binding site (site 1) and induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:25398877). Induces cell proliferation in an integrin-dependent manner (PubMed:18635536).
Subcellular Localization	Cell membrane; Peripheral membrane protein
Description	Boster Bio Anti-PLA2G2A Antibody catalog # A02259. Tested in WB applications. This antibody reacts with Human, Mouse.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A02259-datasheet.pdf

BOS-A02259-safety-datasheet.pdf