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Anti-PEA-15 (D110) Antibody

Anti-PEA-15 (D110) Antibody

ArtNr	BOS-A02988
Hersteller	Boster
Menge	100 ul
Kategorie	Metabolism Diabetes Western Blot
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Alias	Astrocytic phosphoprotein PEA-15,15 kDa phosphoprotein enriched in astrocytes,Phosphoprotein enriched in diabetes,PED,PEA15
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	15040 MW
Clonality	Polyclonal
Application Details	WB: 1:500-1:1000
Gene Name	PEA15
Gene Full Name	Astrocytic phosphoprotein PEA-15
Immunogen	Synthetic peptide, corresponding to amino acids 78-132 of Human PEA-15.
Contents	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Concentration	1 mg/ml
Protein Name	Astrocytic phosphoprotein PEA-15
Protein Function	Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm (By similarity). Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface.
Subcellular Localization	Cytoplasm. Associated with microtubules.
Description	Boster Bio Anti-PEA-15 (D110) Antibody catalog # A02988. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Ubiquitously expressed. Most abundant in tissues such as heart, brain, muscle and adipose tissue which utilize glucose as an energy source. Lower expression in glucose- producing tissues. Higher levels of expression are found in tissues from individuals with type 2 diabetes than in controls.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-A02988-datasheet.pdf

BOS-A02988-safety-datasheet.pdf