Anti-ERAB HSD17B10 Antibody

Primary Antibodies

26923 MW

WB: 1:500-1:2000
IHC: 1:50-1:100
ICC/IF: 1:50-1:100

3-hydroxyacyl-CoA dehydrogenase type-2

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

1 mg/ml

Mitochondrial dehydrogenase that catalyzes the beta-
oxidation at position 17 of androgens and estrogens and has 3-
alpha-hydroxysteroid dehydrogenase activity with androsterone
(PubMed:9553139, PubMed:23042678, PubMed:12917011,
PubMed:18996107, PubMed:25925575, PubMed:28888424). Catalyzes the
third step in the beta-oxidation of fatty acids (PubMed:9553139,
PubMed:12917011, PubMed:18996107, PubMed:25925575,
PubMed:28888424). Carries out oxidative conversions of 7-alpha-OH
and 7-beta-OH bile acids (PubMed:12917011). Also exhibits 20-beta-
OH and 21-OH dehydrogenase activities with C21 steroids
(PubMed:12917011). By interacting with intracellular amyloid-beta,
it may contribute to the neuronal dysfunction associated with
Alzheimer disease (AD) (PubMed:9338779). Essential for structural
and functional integrity of mitochondria (PubMed:20077426).

Boster Bio Anti-ERAB HSD17B10 Antibody catalog # A03844. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.