Anti-JMJD1A KDM3A Antibody

JMJD1A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Polyclonal

KDM3A

The jumonji domain containing 1A protein (JMJD1A) was originally discovered as a testes specific gene, but has been found to be expressed in numerous tissues. JMJD1A is a histone demethylase and specifically demethylates mono- and dimethyl-H3K9. It has also been found to be a novel interaction partner with ER71, a transcription factor expressed in the testes of adult mice and during embryogenesis. JMJD1A is also a downstream gene of STAT3, a protein that has been found to be important in the maintenance of mouse embryonic stem (mES) cells, and decreased JMJD1A expression correlated with the differentiation of cultured mES cells following the removal of the cytokine LIF. These findings suggest that JMJD1A might be a critical signaling molecule underlying the maintenance of pluripotency in embryonic stem cells. At least two isoforms of JMJD1A are known to exist.

JMJD1A Antibody is supplied in PBS containing 0.02% sodium azide.

1 mg/mL

Lysine (K)-specific demethylase 3A

Cytoplasm. Nucleus. Nuclear in round spermatids. When spermatids
start to elongate, localizes to the cytoplasm where it forms
distinct foci which disappear in mature spermatozoa (By
similarity).

Boster Bio Anti-JMJD1A KDM3A Antibody (Catalog # A03994-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Rat.