ArtNr |
BOS-A04185-1-10ug |
Hersteller |
Boster
|
Menge |
10 ug |
Format |
Lyophilized |
Applikationen |
WB, IHC, ELISA |
Specific against |
Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus) |
Host |
Rabbit |
Isotype |
IgG |
Citations |
1. Gao, J.-L., Kuhns, D. B., Tiffany, H. L., McDermott, D., Li, X., Francke, U., Murphy, P. M. Structure and functional expression of the human macrophage inflammatory protein 1 alpha/RANTES receptor. J. Exp. Med. 177: 1421-1427, 1993. 2. Heiber, M., Docherty, J. M., Shah, G., Nguyen, T., Cheng, R., Heng, H. H. Q., Marchese, A., Tsui, L.-C., Shi, X., George, S. R., O'Dowd, B. F. Isolation of three novel human genes encoding G protein-coupled receptors. DNA Cell Biol. 14: 25-35, 1995. 3. Maho, A., Bensimon, A., Vassart, G., Parmentier, M. Mapping of the CCXCR1, CX3CR1, CCBP2 and CCR9 genes to the CCR cluster within the 3p21.3 region of the human genome. Cytogenet. Cell Genet. 87: 265-268, 1999. |
Alias |
NADH-ubiquinone oxidoreductase chain 4; NADH dehydrogenase subunit 4; Mtnd4; mt-Nd4; Nd4 |
Lieferbar |
|
Manufacturer - Category |
Primary Antibodies |
Manufacturer - Isotype |
Rabbit IgG |
Storage Conditions |
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. |
Observed Molecular Weight |
42 kDa |
Clonality |
Polyclonal |
Application Details |
Western blot, 0.25-0.5 ?g/ml, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 ?g/ml, Human, Mouse, Rat
ELISA, 0.1-0.5 ?g/ml, - |
Manufacturer - Gene Name |
XCR1 |
Gene Full Name |
NADH dehydrogenase 4, mitochondrial |
Background |
The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Several alternatively spliced transcript variants encoding the same protein have been found for this gene. |
Immunogen |
E.coli-derived human CCXCR1/XCR1 recombinant protein (Position: F246-N274). |
Contents |
Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4. |
Purification |
Immunogen affinity purified. |
Reconstitution |
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml. |
Concentration |
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml. |
Manufacturer - Research Category |
Cell Type Markers, Tags & Cell Markers |
Protein Function |
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Subcellular Localization |
Mitochondrion membrane. Multi-pass membrane protein. |
Description |
Boster Bio Anti-CCXCR1/XCR1 Antibody Picoband® catalog # A04185-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance. |
Tissue Specificity |
Expressed in lung, on the vascular capillary network within alveolar walls, and also at lower level in kidney. |
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