Item no. |
BOS-A04185-1-10ug |
Manufacturer |
Boster
|
Amount |
10 ug |
Format |
Lyophilized |
Applications |
WB, IHC, ELISA |
Specific against |
Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus) |
Host |
Rabbit |
Isotype |
IgG |
Citations |
1. Gao, J.-L., Kuhns, D. B., Tiffany, H. L., McDermott, D., Li, X., Francke, U., Murphy, P. M. Structure and functional expression of the human macrophage inflammatory protein 1 alpha/RANTES receptor. J. Exp. Med. 177: 1421-1427, 1993. 2. Heiber, M., Docherty, J. M., Shah, G., Nguyen, T., Cheng, R., Heng, H. H. Q., Marchese, A., Tsui, L.-C., Shi, X., George, S. R., O'Dowd, B. F. Isolation of three novel human genes encoding G protein-coupled receptors. DNA Cell Biol. 14: 25-35, 1995. 3. Maho, A., Bensimon, A., Vassart, G., Parmentier, M. Mapping of the CCXCR1, CX3CR1, CCBP2 and CCR9 genes to the CCR cluster within the 3p21.3 region of the human genome. Cytogenet. Cell Genet. 87: 265-268, 1999. |
Alias |
NADH-ubiquinone oxidoreductase chain 4; NADH dehydrogenase subunit 4; Mtnd4; mt-Nd4; Nd4 |
Available |
|
Manufacturer - Category |
Primary Antibodies |
Manufacturer - Isotype |
Rabbit IgG |
Storage Conditions |
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. |
Observed Molecular Weight |
42 kDa |
Clonality |
Polyclonal |
Application Details |
Western blot, 0.25-0.5 ?g/ml, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 ?g/ml, Human, Mouse, Rat
ELISA, 0.1-0.5 ?g/ml, - |
Manufacturer - Gene Name |
XCR1 |
Gene Full Name |
NADH dehydrogenase 4, mitochondrial |
Background |
The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Several alternatively spliced transcript variants encoding the same protein have been found for this gene. |
Immunogen |
E.coli-derived human CCXCR1/XCR1 recombinant protein (Position: F246-N274). |
Contents |
Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4. |
Purification |
Immunogen affinity purified. |
Reconstitution |
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml. |
Concentration |
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml. |
Manufacturer - Research Category |
Cell Type Markers, Tags & Cell Markers |
Protein Function |
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Subcellular Localization |
Mitochondrion membrane. Multi-pass membrane protein. |
Description |
Boster Bio Anti-CCXCR1/XCR1 Antibody Picoband® catalog # A04185-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance. |
Tissue Specificity |
Expressed in lung, on the vascular capillary network within alveolar walls, and also at lower level in kidney. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.