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Anti-FABP-1/GOT2 Antibody Picoband®

Anti-FABP-1/GOT2 Antibody Picoband®

ArtNr	BOS-A05998-1-iFluor647
Hersteller	Boster
Menge	100 ug
Quantity options	100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Kategorie	Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Antibodies Obesity Flow Cytometry Immunohistochemistry Western Blot ELISA Immunofluorescence Immunocytochemistry Lipid & Fatty Acid Transport Primary Antibodies Immunostaining Immunochemistry
Typ	Primary Antibody
Format	Lyophilized
Applikationen	WB, FC, IF, IHC, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	1. Andersson, S. M., Pispa, J. P. Purification and properties of human liver tyrosine aminotransferase. Clin. Chim. Acta 125: 117-123, 1982. 2. Barton, D. E., Yang-Feng, T. L., Francke, U. The human tyrosine aminotransferase gene mapped to the long arm of chromosome 16 (region 16q22-q24) by somatic cell hybrid analysis and in situ hybridization. Hum. Genet. 72: 221-224, 1986. 3. Chen, S.-H., Giblett, E. R. Genetic variation of soluble glutamic-oxaloacetic transaminase in man. Am. J. Hum. Genet. 23: 419-424, 1971.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Tricarboxylate transport protein,mitochondrial,Citrate transport protein,CTP,Solute carrier family 25 member 1,Tricarboxylate carrier protein,SLC25A1,SLC20A3
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Conjugate / Tag	iFluor647
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	41 kDa
Calculated Molecular weight	80420 MW
Clonality	Polyclonal
Application Details	Western blot, 0.1-0.25μg/ml, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5μg/ml, Human Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells, Human ELISA, 0.1-0.5μg/ml
Gene Name	GOT2
Gene Full Name	solute carrier family 25 member 1
Background	Aspartate aminotransferase, mitochondrial is an enzyme that in humans is encoded by the GOT2 gene. Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen	E.coli-derived human FABP-1/GOT2 recombinant protein (Position: H35-K430).
Contents	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category	Cancer, Cell Biology, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction
Protein Name	Long-chain-fatty-acid--CoA ligase 3
Protein Function	Citrate transporter that mediates the exchange of mitochondrial citrate for cytosolic malate. Also able to mediate the exchange of citrate for isocitrate, phosphoenolpyruvate, cis- but not trans-aconitate and to a lesser extend maleate and succinate. Important for the bioenergetics of hepatic cells as it provides a carbon source for fatty acid and sterol biosyntheses, and NAD+ for the glycolytic pathway. Required for proper neuromuscular junction formation (Probable).
Subcellular Localization	Mitochondrion inner membrane. Multi-pass membrane protein.
Description	Boster Bio Anti-FABP-1/GOT2 Antibody Picoband® catalog # A05998-1. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Detected in brain. Detected at very much lower levels in heart, lung, placenta and skeletal muscle. Highly expressed in cerebellum, but also found in frontal cortex, hippocampus and basal ganglia.
Manufacturer - Cross Reactivity	No cross-reactivity with other proteins.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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BOS-A05998-1-iFluor647-datasheet.pdf

BOS-A05998-1-iFluor647-safety-datasheet.pdf