Anti-LRP1B Antibody

ArtNr	BOS-A07425-1-10ug
Hersteller	Boster
Menge	10 ug
Quantity options	100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Kategorie	Oncology Neuroscience Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Antibodies By Cell Type Blastoma Melanoma Obesity Immunohistochemistry ELISA Lipoprotein Receptors & Associated Proteins Lipid & Fatty Acid Transport Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Lyophilized
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	1. Liu, C.-X., Li, Y., Obermoeller-McCormick, L. M., Schwartz, A. L., Bu, G. The putative tumor suppressor LRP1B, a novel member of the low absorbance lipoprotein (LDL) receptor family, exhibits both overlapping and distinct properties with the LDL receptor-related protein. J. Biol. Chem. 276: 28889-28896, 2001. 2. Liu, C.-X., Musco, S., Lisitsina, N. M., Forgacs, E., Minna, J. D., Lisitsyn, N. A. LRP-DIT, a putative endocytic receptor gene, is frequently inactivated in non-small cell lung cancer cell lines. Cancer Res. 60: 1961-1967, 2000. 3. Liu, C.-X., Musco, S., Lisitsina, N. M., Yaklichkin, S. Y., Lisitsyn, N. A. Genomic organization of a new candidate tumor suppressor gene, LRP1B. Genomics 69: 271-274, 2000.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	BAG family molecular chaperone regulator 5,BAG-5,Bcl-2-associated athanogene 5,BAG5,KIAA0873
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Molecular Weight	92 kDa
Calculated Molecular weight	51200 MW
Clonality	Polyclonal
Application Details	Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Human, Mouse, Rat ELISA, 0.1-0.5μg/ml, -
Gene Name	LRP1B
Gene Full Name	BAG family molecular chaperone regulator 5
Manufacturer - Specificity	No cross-reactivity with other proteins.
Background	Low-density lipoprotein receptor-related protein 1B is a protein that in humans is encoded by the LRP1B gene. This gene encodes a member of the low density lipoprotein (LDL) receptor family. These receptors play a wide variety of roles in normal cell function and development due to their interactions with multiple ligands. Disruption of this gene has been reported in several types of cancer.
Immunogen	E.coli-derived human LRP1B recombinant protein (Position: D3704-K4547).
Contents	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2 ml of distilled water will yield a concentration of 500ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category	Interleukins
Protein Name	BAG family molecular chaperone regulator 5
Protein Function	Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2 (By similarity). May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding.
Subcellular Localization	Perinuclear region.
Description	Boster Bio Anti-LRP1B Antibody Picoband® catalog # A07425-1. Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expressed in all tissues examined with lower levels in brain and testis.

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BOS-A07425-1-10ug-datasheet.pdf

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