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Anti-LYPD3 Antibody Picoband® Europäischer Partner

ArtNr BOS-A08396-Cy3
Hersteller Boster
Menge 100 ug
Quantity options 100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Kategorie
Format Lyophilized
Applikationen WB, FC, IF, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Cy3
Citations 1. Fletcher, G. C., Patel, S., Tyson, K., Adam, P. J., Schenker, M., Loader, J. A., Daviet, L., Legrain, P., Parekh, R., Harris, A. L., Terrett, J. A. hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan. Brit. J. Cancer 88: 579-585, 2003.
2. Hansen, L. V., Gardsvoll, H., Nielsen, B. S., Lund, L. R., Dano, K., Jensen, O. N., Ploug, M. Structural analysis and tissue localization of human C4.4A: a protein homologue of the urokinase receptor. Biochem. J. 380: 845-857, 2004.
3. Wurfel, J., Seiter, S., Stassar, M., Claas, A., Klas, R., Rosel, M., Marhaba, R., Savelyeva, L., Schwab, M., Matzku, S., Zoller, M. Cloning of the human homologue of the metastasis-associated rat C4.4A. Gene 262: 35-41, 2001.
Alias 70 kDa ribosomal protein S6 kinase 1 antibody,KS6B1_HUMAN antibody,p70 alpha antibody,P70 beta 1 antibody,p70 ribosomal S6 kinase alpha antibody,p70 ribosomal S6 kinase beta 1 antibody,p70 S6 kinase alpha antibody,P70 S6 Kinase antibody,p70 S6 kinase alpha 1 antibody,p70 S6 kinase alpha 2 antibody,p70 S6K antibody,p70 S6K-alpha antibody,p70 S6KA antibody,p70(S6K) alpha antibody,p70(S6K)-alpha antibody,p70-alpha antibody,p70-S6K 1 antibody,p70-S6K antibody,P70S6K antibody,P70S6K1 antibody,p70S6Kb antibody,PS6K antibody,Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody,Ribosomal protein S6 kinase beta 1 antibody,Ribosomal protein S6 kinase beta-1 antibody,Ribosomal protein S6 kinase I antibody,RPS6KB1 antibody,S6K antibody,S6K-beta-1 antibody,S6K1 antibody,Serine/threonine kinase 14 alpha antibody,Serine/threonine-protein kinase 14A antibody,STK14A antibody
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Manufacturer - Category
Primary Antibodies
Storage Conditions
At -20°C for one year from date of receipt.
After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.
Avoid repeated freezing and thawing.
Observed Molecular weight
75 kDa
Calculated Molecular weight
52588 MW
Clonality
Polyclonal
Application Details
Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Immunohistochemistry, 1-2 μg/ml, Human, Rat
Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/ml
Gene Name
LYPD3
Gene Full Name
Serine/threonine-protein kinase AtPK1/AtPK6
Background
Ly6/PLAUR domain-containing protein 3 is a protein that in humans is encoded by the LYPD3 gene. Ly6 / PLAUR domain-containing protein 3, also known as GPI-anchored metastasis-associated protein C4.4A homolog, Matrigel-induced gene C4 protein, MIG-C4, and LYPD3, is a cell membrane protein that contains two UPAR/Ly6 domains. Human LYPD3 contains two UPAR/Ly6 domains. LYPD3 is expressed in the placenta, skin, and urothelium. It is found in suprabasal keratinocytes of chronic wounds. Weak expression of LYPD3 is found in the esophagus and peripheral blood mononuclear cells. It is found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression of LYPD3 is found in the tumor component of some noninvasive superficial lesions and invasive and metastatic urothelial cancers. LYPD3 is up-regulated in migrating keratinocytes during epithelisation of incisional skin wounds. LYPD3 supports cell migration. It may be involved in urothelial cell-matrix interactions. It may also be involved in tumor progression.
Immunogen
E.coli-derived human ILKAP recombinant protein (Position: E90-H392). Human ILKAP shares 98% and 98.7% amino acid (aa) sequence identity with mouse and rat ILKAP, respectively.
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
Purification
Immunogen affinity purified.
Reconstitution
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category
Signal Transduction, Signaling Pathway, Small G Proteins
Protein Name
Serine/threonine-protein kinase AtPK1/AtPK6
Protein Function
Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway.
Subcellular Localization
Cytoplasm. Nucleus.
Description
Boster Bio Anti-LYPD3 Antibody Picoband® catalog # A08396. Tested in ELISA, IF, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Expressed in all tissues.
Manufacturer - Alias
70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Manufacturer - Cross Reactivity
No cross reactivity with other proteins.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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