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Anti-Forkhead box protein H1 FOXH1 Antibody

Anti-Forkhead box protein H1 FOXH1 Antibody

ArtNr	BOS-A09751-1
Hersteller	Boster
Menge	0.1 mg
Quantity options	100 ul 0.1 mg
Kategorie	Neuroscience Neural Lineage Markers Targets for Rodent Neurosciences Antibodies Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining Neurodegeneration Markers
Typ	Antibody
Format	Liquid
Applikationen	WB, IF, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	FAST1,FAST-1,FAST1,FAST2,Forkhead box protein H1,Forkhead activin signal transducer 1,Fast-1
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	39257 MW
Clonality	Polyclonal
Application Details	FOXH1 antibody can be used for detection of FOXH1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL. Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Gene Name	FOXH1
Gene Full Name	Forkhead box H1
Manufacturer - Specificity	FOXH1 antibody is predicted to not cross-react with any other members of the forkhead box family.
Background	FOXH1 is a member of the Forkhead-box (FOX) family of transcription factors and is the human homolog of Xenopus forkhead activin signal transducer-1. FOXH1 plays an important role in mediating TGF-beta/activin signals through its interaction with the SMAD2-SMAD4 complex. It is expressed primarily during early development and localizes in the cytoplasm until it forms a complex with the SMAD proteins at which time it translocates to the nucleus to positively or negatively affect gene expression.
Immunogen	Rabbit polyclonal FOXH1 antibody was raised against a 19 amino acid peptide near the amino terminus of human FOXH1. The immunogen is located within the first 50 amino acids of FOXH1.
Contents	FOXH1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification	FOXH1 Antibody is affinity chromatography purified via peptide column.
Concentration	1 mg/mL
Manufacturer - Research Category	Stem Cells
Protein Name	Forkhead box H1
Protein Function	Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).
Subcellular Localization	Nucleus.
Description	Boster Bio Anti-Forkhead box protein H1 FOXH1 Antibody (Catalog # A09751-1). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Ubiquitous.
Manufacturer - Cross Reactivity	FOXH1 antibody is predicted to not cross-react with any other members of the forkhead box family.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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BOS-A09751-1-datasheet.pdf

BOS-A09751-1-safety-datasheet.pdf