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Anti-OXER1 Antibody Picoband®

Anti-OXER1 Antibody Picoband®

ArtNr	BOS-A10420-1-Dylight488
Hersteller	Boster
Menge	100 ug
Quantity options	100 ug/vial 10 ug 100 ug/vial 100 ug/vial 100 ug/vial 100 ug 100 ug 100 ug 100 ug/vial 100 ug/vial 100 ug/vial 100 ug/vial
Kategorie	Metabolism Cholesterol & Lipid Metabolism Flow Cytometry Western Blot ELISA Enzymes Immunostaining Leukotriene Metabolism
Format	Lyophilized
Applikationen	WB, FC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	DyLight 488
Citations	1. Dattilo, M., Neuman, I., Munoz, M., Maloberti, P., Cornejo Maciel, F. OxeR1 regulates angiotensin II and cAMP-stimulated steroid production in human H295R adrenocortical cells. Molec. Cell. Endocr. 408: 38-44, 2015 2. Enyedi, B., Kala, S., Nikolich-Zugich, T., Niethammer, P. Tissue damage detection by osmotic surveillance. Nature Cell Biol. 15: 1123-1130, 2013. 3. Hosoi, T., Koguchi, Y., Sugikawa, E., Chikada, A., Ogawa, K., Tsuda, N., Suto, N., Tsunoda, S., Taniguchi, T., Ohnuki, T. Identification of a novel human eicosanoid receptor coupled to G(i/o). J. Biol. Chem. 277: 31459-31465, 2002.
Alias	E3 ubiquitin-protein ligase RNF169,RING finger protein 169,RING-type E3 ubiquitin transferase RNF169,RNF169,KIAA1991
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Observed Molecular weight	43-46 kDa
Calculated Molecular weight	41409 MW
Clonality	Polyclonal
Application Details	Western blot, 0.25-0.5 μg/ml, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/ml
Gene Name	OXER1
Gene Full Name	ring finger protein 169
Background	Oxoeicosanoid receptor 1 (OXER1) also known as G-protein coupled receptor 170 (GPR170) is a protein that in humans is encoded by the OXER1 gene located on human chromosome 2p21; it is the principal receptor for the 5-Hydroxyicosatetraenoic acid family of carboxy fatty acid metabolites derived from arachidonic acid. Enables G protein-coupled receptor activity and icosanoid binding activity. Involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane.
Immunogen	E.coli-derived human OXER1 recombinant protein (Position: M1-Q422).
Contents	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
Purification	Immunogen affinity purified.
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category	Hematopoietic Progenitors, Lymphoid, Stem Cells, T Lymphocytic Lineage
Protein Name	Protein NDRG3
Protein Function	Probable E3 ubiquitin-protein ligase that acts as a negative regulator of double-strand breaks (DSBs) repair following DNA damage. Recruited to DSB repair sites by recognizing and binding ubiquitin catalyzed by RNF168 and competes with TP53BP1 and BRCA1 for association with RNF168-modified chromatin, thereby acting as a negative regulator of DSBs repair. E3 ubiquitin-protein ligase activity is not required for regulation of DSBs repair.
Subcellular Localization	Nucleoplasm.
Description	Boster Bio Anti-OXER1 Antibody Picoband® catalog # A10420-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.
Manufacturer - Cross Reactivity	No cross-reactivity with other proteins.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-A10420-1-Dylight488-datasheet.pdf

BOS-A10420-1-Dylight488-safety-datasheet.pdf