Anti-human CD62L SELL Monoclonal Antibody APC Conjugated, Flow Validated

Store at 2-8°C. Avoid repeated freeze-thaw cycles.

Monoclonal

SELL

L-selectin, also known as CD62L, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17.SELL (L-selectin)is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins.1L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point2.

PBS pH 7.2, 0.2% (w/v) BSA, 0.09% (w/v) sodium azide

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

L-selectin

Membrane; Single-pass type I membrane protein.

Boster Bio Anti-human CD62L SELL Monoclonal Antibody APC Conjugated, Flow Validated (Catalog# FC00652-APC). Tested in Flow Cytometry application(s). This antibody reacts with Human, Baboon.