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Anti-Atg16L1/Atg16 Rabbit Monoclonal Antibody Europäischer Partner

ArtNr BOS-M00526-30ul
Hersteller Boster
Menge 30 ul
Quantity options 100 ul 30 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, IHC
Clon ABIE-1
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Sensitivity >5000 cells
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Autophagy-related protein 16-1,APG16-like 1,ATG16L1,APG16L,UNQ9393/PRO34307
Lieferbar
Manufacturer - Category
Primary Antibodies, Rabbit Monoclonal Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight
68 kDa
Calculated Molecular weight
68265 MW
Clonality
Monoclonal
Application Details
WB 1:500-1:2000
IHC 1:50-1:200
Gene Name
ATG16L1
Gene Full Name
Autophagy-related protein 16-1
Immunogen
A synthesized peptide derived from human Atg16L1
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification
Affinity-chromatography
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category
Cancer, Cardiovascular, Cell Biology, Cell Death, Metabolism, Metabolism Processes, Neurodegenerative Disease, Neurology Process, Neuroscience, Oncoproteins/Suppressors, Pathways and Processes, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Signal Transduction, Tumor Suppressors, Ub-Like Proteins
Protein Name
T-cell surface glycoprotein CD4
Protein Function
Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
Subcellular Localization
Cytoplasm. Preautophagosomal structure membrane ; Peripheral membrane protein. Recruited to omegasomes membranes by WIPI2. Omegasomes are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures. Localized to preautophagosomal structure (PAS) where it is involved in the membrane targeting of ATG5. Localizes also to discrete punctae along the ciliary axoneme.
Description
Boster Bio Anti-Atg16L1/Atg16 Rabbit Monoclonal Antibody catalog # M00526. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity
Plasma. Synthesized by the fetal liver and yolk sac.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 30 ul
Lieferbar: In stock
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