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Anti-Desmoglein 2 Monoclonal Antibody

Anti-Desmoglein 2 Monoclonal Antibody

ArtNr	BOS-M02035-30ul
Hersteller	Boster
Menge	30 ul
Quantity options	100 ul 30 ul
Kategorie	Antibodies Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies Immunochemistry
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, FC, IF, IHC, ICC
Clon	AFBF-4
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	<10 pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Melanoma antigen recognized by T-cells 1,MART-1,Antigen LB39-AA,Antigen SK29-AA,Protein Melan-A,MLANA,MART1
Lieferbar
Manufacturer - Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	42 kDa
Calculated Molecular weight	13157 MW
Clonality	Monoclonal
Application Details	WB 1:1000-1:5000 IHC 1:50-1:200 ICC/IF 1:50-1:200 FC 1:100
Gene Name	DSG2
Gene Full Name	Melanoma antigen recognized by T-cells 1
Immunogen	A synthesized peptide derived from human Desmoglein 2 Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Cadherins, Cancer, Cardiovascular, Cell Adhesion, Cytoskeleton/ECM, Invasion/Microenvironment, Signal Transduction
Protein Name	Lysosome-associated membrane glycoprotein 2 (Lamp2)
Protein Function	Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
Subcellular Localization	Endoplasmic reticulum membrane; Single-pass type III membrane protein. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane. Melanosome. Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post- Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation.
Description	Boster Bio Anti-Desmoglein 2 Monoclonal Antibody catalog # M02035. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expression is restricted to melanoma and melanocyte cell lines and retina.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-M02035-30ul-datasheet.pdf

BOS-M02035-30ul-safety-datasheet.pdf