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Anti-ADK Rabbit Monoclonal Antibody Europäischer Partner

ArtNr BOS-M02193-2-30ul
Hersteller Boster
Menge 30 ul
Format Liquid
Applikationen WB
Clon 25A83
Specific against Human (Homo sapiens), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Sensitivity <10pg/ml
Alias Caspase-10;CASP-10;3.4.22.63;Apoptotic protease Mch-4;FAS-associated death domain protein interleukin-1B-converting enzyme 2;FLICE2;ICE-like apoptotic protease 4;Caspase-10 subunit p23/17;Caspase-10 subunit p12;CASP10;MCH4;
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Manufacturer - Category
Rabbit Monoclonal Antibodies
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
45 kDa
Calculated Molecular weight
58951 MW
Clonality
Monoclonal
Application Details
WB 1:500-1:2000
Manufacturer - Gene Name
ADK
Gene Full Name
Caspase-10
Immunogen
A synthesized peptide derived from human ADK
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification
Affinity-chromatography
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category
Nucleus, Subcellular Markers, Tags & Cell Markers
Protein Name
Lysosome-associated membrane glycoprotein 2 (Lamp2)
Protein Function
Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase- 3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC.
Subcellular Localization
Cytoplasm. Nucleus. Cell membrane. Membrane, clathrin-coated pit. Cell projection, pseudopodium. Cytoplasmic vesicle. Translocates to the plasma membrane and colocalizes with antagonist-stimulated GPCRs. The monomeric form is predominantly located in the nucleus. The oligomeric form is located in the cytoplasm. Translocates to the nucleus upon stimulation of OPRD1 (By similarity).
Description
Boster Bio Anti-ADK Rabbit Monoclonal Antibody catalog # M02193-2. Tested in WB application. This antibody reacts with Human, Rat.
Tissue Specificity
Detectable in most tissues. Lowest expression is seen in brain, kidney, prostate, testis and colon.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 30 ul
Lieferbar: In stock
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