Item no. |
BOS-M02193-2-30ul |
Manufacturer |
Boster
|
Amount |
30 ul |
Format |
Liquid |
Applications |
WB |
Clone |
25A83 |
Specific against |
Human (Homo sapiens), Rat (Rattus norvegicus) |
Host |
Rabbit |
Isotype |
IgG |
Sensitivity |
<10pg/ml |
Alias |
Caspase-10;CASP-10;3.4.22.63;Apoptotic protease Mch-4;FAS-associated death domain protein interleukin-1B-converting enzyme 2;FLICE2;ICE-like apoptotic protease 4;Caspase-10 subunit p23/17;Caspase-10 subunit p12;CASP10;MCH4; |
Available |
|
Manufacturer - Category |
Rabbit Monoclonal Antibodies |
Storage Conditions |
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Observed Molecular Weight |
45 kDa |
Calculated Molecular weight |
58951 MW |
Clonality |
Monoclonal |
Application Details |
WB 1:500-1:2000 |
Manufacturer - Gene Name |
ADK |
Gene Full Name |
Caspase-10 |
Immunogen |
A synthesized peptide derived from human ADK |
Contents |
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA. |
Purification |
Affinity-chromatography |
Reconstitution |
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL |
Concentration |
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
Manufacturer - Research Category |
Nucleus, Subcellular Markers, Tags & Cell Markers |
Protein Name |
Lysosome-associated membrane glycoprotein 2 (Lamp2) |
Protein Function |
Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase- 3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC. |
Subcellular Localization |
Cytoplasm. Nucleus. Cell membrane. Membrane, clathrin-coated pit. Cell projection, pseudopodium. Cytoplasmic vesicle. Translocates to the plasma membrane and colocalizes with antagonist-stimulated GPCRs. The monomeric form is predominantly located in the nucleus. The oligomeric form is located in the cytoplasm. Translocates to the nucleus upon stimulation of OPRD1 (By similarity). |
Description |
Boster Bio Anti-ADK Rabbit Monoclonal Antibody catalog # M02193-2. Tested in WB application. This antibody reacts with Human, Rat. |
Tissue Specificity |
Detectable in most tissues. Lowest expression is seen in brain, kidney, prostate, testis and colon. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.