« Zurück
Startseite /
Anti-SMURF 2 Rabbit Monoclonal Antibody

Anti-SMURF 2 Rabbit Monoclonal Antibody

ArtNr	BOS-M02585-30ul
Hersteller	Boster
Menge	30 ul
Quantity options	100 ul 30 ul
Kategorie	Antibodies Cell Biology Cell Status Western Blot Senescence Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB
Clon	AECF-19
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	<20 pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Neurogenic locus notch homolog protein 4,Notch 4,hNotch4,Notch 4 extracellular truncation,Notch 4 intracellular domain,NOTCH4,INT3
Lieferbar
Manufacturer - Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	41 kDa
Calculated Molecular weight	209622 MW
Clonality	Monoclonal
Application Details	WB 1:500-1:1000
Gene Name	SMURF2
Gene Full Name	Neurogenic locus notch homolog protein 4
Immunogen	A synthesized peptide derived from human SMURF 2 E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then ly transfers the ubiquitin to targeted substrates. Interacts with SMAD1 and SMAD7 in order to trigger their ubiquitination and proteasome-dependent degradation.
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Cardiogenesis, Cardiovascular, Epigenetics and Nuclear Signaling, Nuclear, Signaling Pathways, Stem Cells, Surface Molecules, Transcription, Transcription Factors/Regulators
Protein Name	T-cell surface glycoprotein CD3 zeta chain
Protein Function	Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity).
Subcellular Localization	Cell membrane; Single-pass type I membrane protein.
Description	Boster Bio Anti-SMURF 2 Rabbit Monoclonal Antibody catalog # M02585. Tested in WB application. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Highly expressed in the heart, moderately in the lung and placenta and at low levels in the liver, skeletal muscle, kidney, pancreas, spleen, lymph node, thymus, bone marrow and fetal liver. No expression was seen in adult brain or peripheral blood leukocytes.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-M02585-30ul-datasheet.pdf

BOS-M02585-30ul-safety-datasheet.pdf