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Anti-Angiotensinogen/AGT Antibody Picoband® Europäischer Partner

ArtNr BOS-PA1643-Dylight594
Hersteller Boster
Menge 100 ug
Quantity options 100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Kategorie
Typ Antibody Polyclonal
Format Lyophilized
Applikationen WB, IHC
Specific against Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Konjugat/Tag DyLight 594
Sensitivity >5000 cells
Sequence Belongs to the ku70 family.
Citations 1. Abonia, J. P., Abel, K. J., Eddy, R. L., Elliott, R. W., Chapman, V. M., Shows, T. B., Gross, K. W. Linkage of Agt and Actsk-1 to distal mouse chromosome 8 loci: a new conserved linkage. Mammalian Genome 4: 25-32, 1993.
2. Arakawa, K., Minohara, A., Yamada, J., Nakamura, M. Enzymatic degradation and electrophoresis of human angiotensin I. Biochim. Biophys. Acta 168: 106-112, 1968.
3. Basso N, Terragno NA (December 2001). History about the discovery of the renin-angiotensin system. Hypertension 38 (6): 1246–9.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Angiotensinogen,Serpin A8,Angiotensin-1,Angiotensin 1-10,Angiotensin I,Ang I,Angiotensin-2,Angiotensin 1-8,Angiotensin II,Ang II,Angiotensin-3,Angiotensin 2-8,Angiotensin III,Ang III,Des-Asp[1]-angiotensin II,Angiotensin-4,Angiotensin 3-8,Angiotensin IV,Ang IV,Angiotensin 1-9,Angiotensin 1-7,Angiotensin 1-5,Angiotensin 1-4,Agt,Serpina8
Lieferbar
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight
55 kDa
Calculated Molecular weight
51990 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5μg/ml, Mouse
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Mouse
Gene Name
AGT
Gene Full Name
Angiotensinogen
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
AGT (ANGIOTENSINOGEN), also called SERPINA8, is an alpha-2-globulin that is produced constitutively and released into the circulation mainly by the liver. ATG is a member of the serpin family, although it is not known to inhibit other enzymes, unlike most serpins. Angiotensinogen is also known as renin substrate. The AGT gene is mapped on 1q42.2. And the human angiotensinogen gene contains 5 exons. The expression of AGT and enzymes required for its conversion to angiotensin II in human adipose tissue. Western blot analysis showed a distinct band of expected size of the angiotensinogen protein (61 kD) in isolated adipocytes. The more pronounced AGT increase in TT subjects resulted in similar plasma renin activity at a lower plasma active renin concentration, with a higher plasma renin activity/active renin ratio.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of mouse Angiotensinogen, identical to the related rat sequence.
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category
Cardiovascular, G Protein Signaling, Signal Transduction, Signaling Pathway
Protein Name
Angiotensinogen
Protein Function
Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
Subcellular Localization
Secreted.
Description
Boster Bio Anti-Angiotensinogen/AGT Antibody catalog # PA1643. Tested in IHC, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Expressed by the liver and secreted in plasma.
Sequence Similarities
Belongs to the ku70 family.
Manufacturer - Alias
Angiotensinogen, Serpin A8, Angiotensin-1, Angiotensin 1-10, Angiotensin I, Ang I, Angiotensin-2, Angiotensin 1-8, Angiotensin II, Ang II, Angiotensin-3, Angiotensin 2-8, Angiotensin III, Ang III, Des-Asp[1]-angiotensin II, Angiotensin-4, Angiotensin 3-8, Angiotensin IV, Ang IV, Angiotensin 1-9, Angiotensin 1-7, Angiotensin 1-5, Angiotensin 1-4, Agt, Serpina8
Manufacturer - Cross Reactivity
No cross-reactivity with other proteins

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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