Anti-HSPA2 Antibody Picoband®

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

70021 MW

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Heat shock-related 70 kDa protein 2

HSPA2 (heat shock 70kDa protein 2) also known as HEAT-SHOCK PROTEIN, 70-KD, 2, HSP70-2, HEAT-SHOCK PROTEIN, 70-KD, 3 or HSP70-3. Analysis of the sequence indicated that  HSPA2  is the human homolog of the murine Hsp70-2 gene, with 91.7% identity in the nucleotide coding sequence and 98.2% in the corresponding amino acid sequence.HSPA2  has less amino acid homology to the other members of the human HSP70 gene family.  HSPA2  is constitutively expressed in most tissues, with very high levels in testis and skeletal muscle. The  HSPA2  gene is located on chromosome 14q22-q24. Immunohistochemical analysis detected weak expression of  HSPA2  in spermatocytes and stronger expression in spermatids and in the tail of mature sperm. HSPA2  may be critical to sperm maturation through its role as a protein chaperone.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Cancer, Chaperones, Heat Shock Proteins, Protein Trafficking, Signal Transduction, Tumor Biomarkers

In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.

Boster Bio Anti-HSPA2 Antibody catalog # PA1814. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Belongs to the heat shock protein 70 family.