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Anti-alpha 1 Fetoprotein/AFP Antibody Picoband® Europäischer Partner

ArtNr BOS-PB9090-carrier-free
Hersteller Boster
Menge 100 ug
Quantity options 100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Kategorie
Typ Antibody Polyclonal
Format Lyophilized
Applikationen WB, IHC
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Sensitivity <5 pg/ml
Sequence Belongs to the ALB/AFP/VDB family.
Citations 1. Carter CS (2002). Neuroendocrinology of sexual behavior in the female. In Becker JB. Behavioral Endocrinology. Cambridge, Mass: MIT Press. pp.88-89. ISBN 0-262-52321-3
2. Bader D, Riskin A, Vafsi O, Tamir A, Peskin B, Israel N, Merksamer R, Dar H, David M (November 2004). Alpha-fetoprotein in the early neonatal period--a large study and review of the literature. Clin. Chim. Acta 349 (1-2): 15–23.
3. Blair JI, Carachi R, Gupta R, Sim FG, McAllister EJ, Weston R (April 1987). Plasma alpha fetoprotein reference ranges in infancy: effect of prematurity. Arch. Dis. Child. 62 (4): 362–9.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Alpha-fetoprotein,Alpha-1-fetoprotein,Alpha-fetoglobulin,AFP,HPAFP
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Conjugate / Tag
carrier-free
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight
69 kDa
Calculated Molecular weight
68678 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5μg/ml, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human
Gene Name
AFP
Gene Full Name
Alpha-fetoprotein
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
AFP, also called Alpha-fetoprotein; alpha-fetoprotein, is a protein that in humans is encoded by the AFP gene. It is mapped to 4q13.3. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. In rodents AFP binds estradiol to prevent the transport of this hormone across the placenta to the fetus. The main function of this is to prevent the virilization of female fetuses. Moreover, it has an important role as a diagnostic marker, especially in certain tumors and liver diseases of childhood. AFP is also used to test the potential usefulness of plasma alpha fetoprotein determination as a diagnostic marker in biliary atresia, hepatitis, and yolk sac derived tumours.
Immunogen
E.coli-derived human AFP recombinant protein (Position: Q378-V609). Human AFP shares 71% and 73% amino acid (aa) sequences identity with mouse and rat AFP, respectively.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category
Cancer, Cardiovascular, Developmental Biology, Organogenesis, Serum Proteins, Tumor Antigens, Tumor Biomarkers
Protein Name
Alpha-fetoprotein
Protein Function
Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.
Subcellular Localization
Secreted.
Description
Boster Bio Anti-alpha 1 Fetoprotein/AFP Antibody Picoband® catalog # PB9090. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Plasma. Synthesized by the fetal liver and yolk sac.
Sequence Similarities
Belongs to the ALB/AFP/VDB family.
Manufacturer - Cross Reactivity
No cross-reactivity with other proteins

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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