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Anti-SFRP2 Antibody Picoband® Europäischer Partner

ArtNr BOS-PB9362-Dylight594
Hersteller Boster
Menge 100 ug
Quantity options 100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Kategorie
Typ Antibody Polyclonal
Format Lyophilized
Applikationen WB, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag DyLight 594
Sensitivity <5 pg/ml
Sequence Belongs to the secreted frizzled-related protein (sFRP) family.
Citations 1. Hao XW, et al. Epigenetic inactivation of secreted frizzled-related protein 2 in esophageal squamous cell carcinoma. World J Gastroenterol, 2012 Feb 14.
2. O'Hurley G, et al. The role of secreted frizzled-related protein 2 expression in prostate cancer. Histopathology, 2011 Dec.
3. Sui C, et al. Variation risks of SFRP2 hypermethylation between precancerous disease and colorectal cancer. Tumour Biol, 2014 Oct.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Secreted frizzled-related protein 2,FRP-2,sFRP-2,Secreted apoptosis-related protein 1,SARP-1,SFRP2,FRP2,SARP1,FKSG12,UNQ361/PRO697
Lieferbar
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight
33 kDa
Calculated Molecular weight
33490 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5μg/ml, Human, -
ELISA, 0.1-0.5μg/ml
Gene Name
SFRP2
Gene Full Name
Secreted frizzled-related protein 2
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
SFRP2 is also known as FRP-2, SARP1 or SDF-5. It is Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon. This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.?
Immunogen
E.coli-derived human SFRP2 recombinant protein (Position: L104-C295). Human SFRP2?shares?99%?amino?acid?(aa)?sequence?identity?with mouse SFRP2.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category
Angiogenesis, Cancer, Cardiogenesis, Cardiovascular, Invasion/Microenvironment, Mesenchymal Stem Cells, Secreted, Signaling Pathways, Stem Cells, Transcription Factors/Regulators
Protein Name
Secreted frizzled-related protein 2
Protein Function
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.
Subcellular Localization
Secreted.
Description
Boster Bio Anti-SFRP2 Antibody Picoband® catalog # PB9362. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon.
Sequence Similarities
Belongs to the secreted frizzled-related protein (sFRP) family.
Manufacturer - Cross Reactivity
No cross-reactivity with other proteins.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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