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Anti-Glucose Transporter GLUT2/SLC2A2 Antibody Picoband® Europäischer Partner

ArtNr BOS-PB9436-Biotin
Hersteller Boster
Menge 100 ug
Quantity options 100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Kategorie
Typ Antibody Polyclonal
Format Lyophilized
Applikationen WB, IHC
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag Biotin
Sensitivity >5000 cells
Sequence Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
Citations 1. Froguel P, Zouali H, Sun F, Velho G, Fukumoto H, Passa P, Cohen D (July 1991).CA repeat polymorphism in the glucose transporter GLUT 2 gene. Nucleic Acids Res. 19 (13): 3754.
2. Santer R, Groth S, Kinner M, Dombrowski A, Berry GT, Brodehl J, Leonard JV, Moses S, Norgren S, Skovby F, Schneppenheim R, Steinmann B, Schaub J (January 2002). The mutation spectrum of the facilitative glucose transporter gene SLC2A2 (GLUT2) in patients with Fanconi-Bickel syndrome.Hum. Genet. 110 (1): 21–9.
3. Uldry M, Ibberson M, Hosokawa M, Thorens B (July 2002). GLUT2 is a high affinity glucosamine transporter. FEBS Lett. 524(1-3): 199–203.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Solute carrier family 2,facilitated glucose transporter member 2,Glucose transporter type 2,liver,GLUT-2,SLC2A2,GLUT2
Lieferbar
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight
50 kDa
Calculated Molecular weight
57490 MW
Clonality
Polyclonal
Application Details
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human
Western blot, 0.1-0.5μg/ml, Human
Gene Name
SLC2A2
Gene Full Name
Solute carrier family 2, facilitated glucose transporter member 2
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
SLC2A2, also known as Glucose transporter 2 (GLUT2), is a transmembrane carrier protein that enables protein facilitatedglucose movement across cell membranes. This gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated biional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM). Alternative splicing results in multiple transcript variants of this gene.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human SLC2A2, different from the related mouse sequence by five amino acids, and from the related rat sequence by seven amino acids.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category
Cancer, Cancer Metabolism, Carbohydrate Metabolism, Developmental Biology, Energy Metabolism, Energy Transfer Pathways, Lineage Markers, Lineage Specification, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Metabolism Of Carbohydrates, Metabolism of Lipids and Lipoproteins, Pathways and Processes, Signal Transduction, Stem Cells
Protein Name
Solute carrier family 2, facilitated glucose transporter member 2
Protein Function
Facilitative glucose transporter. This isoform likely mediates the biional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na (+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.
Subcellular Localization
Membrane; Multi-pass membrane protein.
Description
Boster Bio Anti-Glucose Transporter GLUT2/SLC2A2 Antibody Picoband® catalog # PB9436. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Liver, insulin-producing beta cell, small intestine and kidney.
Sequence Similarities
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
Manufacturer - Cross Reactivity
No cross-reactivity with other proteins

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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