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Anti-Interleukin-13 IL13 Antibody Europäischer Partner

ArtNr BOS-RP1048-Cy3
Hersteller Boster
Menge 100 ug
Quantity options 100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Kategorie
Typ Antibody Polyclonal
Format Lyophilized
Applikationen ELISA
Specific against Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Cy3
Sensitivity <1 pg/ml
Sequence Belongs to the IL-4/IL-13 family.
Citations 1. Blackburn, M. R., Lee, C. G., Young, H. W. J., Zhu, Z., Chunn, J. L., Kang, M. J., Banerjee, S. K., Elias, J. A.Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway.
2. Paul, W. E.Personal Communication.Bethesda, Md. 3/6/1993.
3. Punnonen, J., Aversa, G., Cocks, B. G., McKenzie, A. N. J., Menon, S., Zurawski, G., de Waal Malefyt, R., de Vries, J. E.Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.Proc. Nat. Acad. Sci. 90: 3730-3734, 1993.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Interleukin-13,IL-13,T-cell activation protein P600,Il13,Il-13
Lieferbar
Manufacturer - Applications
ELISA (Cap)
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight
37 kDa
Calculated Molecular weight
14093 MW
Clonality
Polyclonal
Application Details
ELISA(Cap), 0.1-0.5μg/ml, Rat
Gene Name
IL13
Gene Full Name
Interleukin-13
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
IL-13, Interleukin 13, is a protein that in humans is encoded by the IL-13 gene. IL-13 is a kind of cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, which is an important mediator of allergic inflammation and disease. The IL-13 gene is mapped to 5q23-q31. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains. This gene acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.
Immunogen
E. coli-derived rat IL-13 recombinant protein (Position: P22-H131). Rat IL-13 shares 62% and 76% amino acid (aa) sequence identity with human and mouse IL-13, respectively.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category
Cytokines, Immunology, Innate Immunity, Interleukins
Protein Name
Interleukin-13
Protein Function
Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses (By similarity).
Subcellular Localization
Secreted.
Description
Boster Bio Anti-Interleukin-13 IL13 Antibody catalog # RP1048. Tested in ELISA applications. This antibody reacts with Rat.
Tissue Specificity
Activated T-cells, mast cells, natural killer cells.
Sequence Similarities
Belongs to the IL-4/IL-13 family.
Manufacturer - Cross Reactivity
No cross-reactivity with other proteins

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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