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Anti-CEACAM5/Cd66e Monoclonal Antibody

Anti-CEACAM5/Cd66e Monoclonal Antibody

ArtNr	BOS-MA1023
Hersteller	Boster
Menge	100 ug/vial
Quantity options	100 ug/vial 10 ug
Kategorie	Oncology Antibodies By Cell Type Carcinoma Hematology Leukemia Immunohistochemistry Western Blot Primary Antibodies By Organ Lung Cancer Bladder Cancer Colorectal Cancer Breast Cancer Testicular & Prostate Cancer Gallbladder Cancer Gastric Cancer Pancreatic Cancer Thyroid Cancer
Typ	Antibody Monoclonal
Format	Lyophilized
Applikationen	WB, IHC
Clon	C6G9
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Sensitivity	>5000 cells
Sequence	Belongs to the immunoglobulin superfamily. CEA family.
Citations	1. Barnett, T.; Goebel, S. J.; Nothdurft, M. A.; Elting, J. J. : Carcinoembryonic antigen family: characterization of cDNAs coding for NCA and CEA and suggestion of nonrandom sequence variation in their conserved loop-domains. Genomics 3: 59-66, 1988. 2. Gold, P.; Freedman, S. O. : Demonstration of tumor-specific antigens in human colonic carcinomata by immunological tolerance and absorption techniques. J. Exp. Med. 121: 439-462, 1965.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Carcinoembryonic antigen-related cell adhesion molecule 5,Carcinoembryonic antigen,CEA,Meconium antigen 100,CD66e,CEACAM5
Similar products	CD66a, BGP, BGP1, Biliary glycoprotein 1
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Manufacturer - Category	Primary Antibodies, Mouse Monoclonal Antibodies
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	37 kDa
Calculated Molecular weight	37141 MW
Clonality	Monoclonal
Application Details	Immunohistochemistry (Paraffin-embedded Section), 0.5-2μg/ml, Human Western blot, 0.5-1μg/ml, Human
Gene Name	CEACAM1
Gene Full Name	Carcinoembryonic antigen-related cell adhesion molecule 5
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	Carcinoembryonic antigen is a complex immunoreactive glycoprotein with a molecular weight of 180, 000 comprising 60% carbohydrate. It is found in adenocarcinomas of endodermally derived digestive system epithelia and in fetal colon.Carcinoembryonic antigen is one of the most widely used tumor markers in serum immunoassay determinations of carcinoma.
Immunogen	Carcinoembryonic antigen-related cell adhesion molecule 5 (CEA) isolated from a human colon adenocarcinoma cell line.
Contents	Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Purification	Ascites
Reconstitution	Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Concentration	Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.
Manufacturer - Research Category	Cancer, Cell Type Markers, Human Protein, Microbiology, Oncoproteins/Suppressors, Protein, Tags & Cell Markers, Tumor Antigens, Tumor Associated, Tumor Biomarkers, Tumor Immunology, Tumor Suppressors, Tumor-Associated Antigens
Protein Name	Carcinoembryonic antigen-related cell adhesion molecule 5
Protein Function	Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:2803308, PubMed:10910050, PubMed:10864933). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:2803308). Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells
Subcellular Localization	Cell membrane
Description	Boster Bio Anti-CEACAM5/Cd66e Monoclonal Antibody catalog # MA1023. Tested in IHC, WB applications. This antibody reacts with Human.
Tissue Specificity	Expressed in columnar epithelial and goblet cells of the colon (at protein level) (PubMed:10436421). Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
Sequence Similarities	Belongs to the immunoglobulin superfamily. CEA family.
Manufacturer - Cross Reactivity	No cross-reactivity with other proteins

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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BOS-MA1023-datasheet.pdf

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