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Anti-Lipocalin-1 LCN1 Antibody Picoband® Europäischer Partner

ArtNr BOS-PA1659
Hersteller Boster
Menge 100 ug/vial
Kategorie
Typ Antibody Polyclonal
Format Lyophilized
Applikationen WB, IHC
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Sensitivity >5000 cells
Citations 1. Baumgartner, M., Holzfeind, P., Redl, B. Assignment of the gene for human tear prealbumin (LCN1), a member of the lipocalin superfamily, to chromosome 8q24. Cytogenet. Cell Genet. 65: 101-103, 1994.
2. Blaker, M., Kock, K., Ahlers, C., Buck, F., Schmale, H. Molecular cloning of human von Ebner's gland protein, a member of the lipocalin superfamily highly expressed in lingual salivary glands. Biochim. Biophys. Acta 1172: 131-137, 1993.
3. Glasgow BJ, Abduragimov AR, Gasymov OK, Yusifov TN (2003). "Tear lipocalin: structure, function and molecular mechanisms of action". Adv. Exp. Med. Biol. 506 (Pt A): 555–65.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Lipocalin-1;Tear lipocalin;Tlc;Tear prealbumin;TP;Von Ebner gland protein;VEG protein;LCN1;VEGP;
Similar products LCN1 antibody, LCN1_HUMAN antibody, Lipocalin 1(protein migrating faster than albumin, tear prealbumin) antibody, Lipocalin 1 like 2 antibody, Lipocalin-1 antibody, PMFA antibody, Tear lipocalin antibody, Tear prealbumin antibody, Tlc antibody, TP antibody, VEG protein antibody, VEGP antibody, Von Ebner gland protein antibody
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
19 kDa
Calculated Molecular weight
19250 MW
Clonality
Polyclonal
Application Details
Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml, Human, By Heat
Western blot, 0.1-0.5?g/ml, Human
Manufacturer - Gene Name
LCN1
Gene Full Name
Lipocalin-1
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
Lipocalin-1 (LCN1), also known as PREALBUMIN, TEAR or VEGP, is a protein that in humans is encoded by the LCN1 gene. Lipocalin-1 is a member of the lipocalin family of small secretory proteins, which is mapped on 9q34.3. Lipocalin-1 is the primary lipid binding protein in tears and is overproduced in response to multiple stimuli including infection and stress. It may be a marker for chromosome aneuploidy as well as an autoantigen in Sjogren's syndrome. LCN1 inhibits the cysteine-protease papain in vitro, similar to cystatins. And LCN1 plays a role in the nonimmunologic defense and in the control of inflammatory processes in oral and ocular tissues. The investigations presented the first clear evidence that LCN1 is induced in infection or inflammation and supported the idea that this lipocalin functions as a physiologic protection factor of epithelia in vivo.
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human LCN1.
Contents
Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
Cell Biology, Neuroscience, Protease Inhibitors, Proteolysis/Ubiquitin, Sensory System
Protein Name
Lipocalin-1
Protein Function
Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket.
Subcellular Localization
Secreted.
Description
Boster Bio Anti-Lipocalin-1 LCN1 Antibody catalog # PA1659. Tested in IHC, WB applications. This antibody reacts with Human.
Tissue Specificity
Mainly expressed in lachrymal and salivary glands. Also expressed in the prostate.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
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