Anti-TNFAIP8L3 Antibody Picoband®

ArtNr	BOS-PA2257
Hersteller	Boster
Menge	100 ug/vial
Kategorie	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Antibodies By Cell Type Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Format	Lyophilized
Applikationen	WB, IHC
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Sensitivity	>5000 cells
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Tumor necrosis factor alpha-induced protein 8-like protein 3;TNF alpha-induced protein 8-like protein 3;TNFAIP8-like protein 3;TNFAIP8L3;
Similar products	9930029P06Rik antibody, FLJ41287 antibody, Gm517 antibody, MGC141255 antibody, RGD1311533 antibody, TNF alpha-induced protein 8-like protein 3 antibody, TNFAIP8-like protein 3 antibody, tnfaip8l3 antibody, TP8L3_HUMAN antibody, Tumor necrosis factor alpha-induced protein 8-like protein 3 antibody
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Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	33 kDa
Calculated Molecular weight	32659 MW
Clonality	Polyclonal
Application Details	Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml, Human, By Heat Western blot, 0.1-0.5?g/ml, Human
Manufacturer - Gene Name	TNFAIP8L3
Gene Full Name	Tumor necrosis factor alpha-induced protein 8-like protein 3
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	TNFAIP8L3 belongs to the TNFAIP8 family. It acts as a negative mediator of apoptosis and may play a role in tumor progression. This gene suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
Immunogen	A synthetic peptide corresponding to a sequence at the C-terminus of human TNFAIP8L3, different from the related mouse and rat sequences by two amino acids.
Contents	Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category	Cell Biology
Protein Name	Tumor necrosis factor alpha-induced protein 8-like protein 3
Protein Function	Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.
Subcellular Localization	Secreted, extracellular space.
Description	Boster Bio Anti-TNFAIP8L3 Antibody catalog # PA2257. Tested in IHC, WB applications. This antibody reacts with Human.
Tissue Specificity	Plasma, associated with HDL (at protein level). Expressed in liver, but not in heart, brain, placenta, lung, skeletal muscle, kidney or pancreas.
Sequence Similarities	Belongs to the TNFAIP8 family.

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BOS-PA2257-datasheet.pdf

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