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Anti-Rab9/RAB9A Antibody Picoband® Europäischer Partner

ArtNr BOS-PA2281
Hersteller Boster
Menge 100 ug/vial
Kategorie
Typ Antibody Polyclonal
Format Lyophilized
Applikationen WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Sensitivity >5000 cells
Citations 1. Carroll, K. S., Hanna, J., Simon, I., Krise, J., Barbero, P., Pfeffer, S. R. Role of Rab9 GTPase in facilitating receptor recruitment by TIP47. Science 292: 1373-1376, 2001.
2. Davies, J. P., Cotter, P. D., Ioannou, Y. A. Cloning and mapping of human Rab7 and Rab9 cDNA sequences and identification of a Rab9 pseudogene. Genomics 41: 131-134, 1997.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Ras-related protein Rab-9A;RAB9A;RAB9;
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Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
23 kDa
Calculated Molecular weight
22838 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5?g/ml, Human, Mouse, Rat
Manufacturer - Gene Name
RAB9A
Gene Full Name
Ras-related protein Rab-9A
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
Ras-related protein Rab-9A, also called RAB9, is a protein that in humans is encoded by the RAB9A gene. This gene is mapped to Xp22.2. RAB9 has been localized to components of the endocytic/exocytic pathway and has been implicated in recycling of membrane receptors. It has been found that downregulation of RAB9A gene expression in HeLa cells induced severe cell vacuolation. RAB9A GTPase is ly bound by TIP47 in its active, GTP-bound conformation. Moreover, RAB9A increases the affinity of TIP47 for its cargo. What's more, this gene may involved in the transport of proteins between the endosomes and the trans Golgi network. RAB9A has been shown to interact with RABEPK and TIP47.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Rab9, identical to the related rat sequence, and different from the related mouse sequence by one amino acid.
Contents
Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
G Protein Signaling, Organelles, Protein Trafficking, Ras Family, Signal Transduction, Signaling Pathway, Small G Proteins, Subcellular Markers, Tags & Cell Markers, Vesicle Transport
Protein Name
Ras-related protein Rab-9A
Protein Function
Involved in the transport of proteins between the endosomes and the trans Golgi network.
Subcellular Localization
Cell membrane; Lipid-anchor; Cytoplasmic side. Endoplasmic reticulum membrane. Golgi apparatus membrane. Late endosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, phagosome. Colocalizes with OSBPL1A at the late endosome. Recruited to phagosomes containing S.aureus or M.tuberculosis.
Description
Boster Bio Anti-Rab9/RAB9A Antibody catalog # PA2281. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
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