Anti-Angiostatin K1-3/PLG Antibody Picoband®

Primary Antibodies

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

90569 MW

Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml, Human, By Heat

ELISA, 0.1-0.5?g/ml, -
Western blot, 0.1-0.5?g/ml, Human

Plasminogen

Ang K1-3 is a single, non-glycosylated polypeptide chain containing 259 amino acids. It represents a proteolytic fragment of plasminogen containing the first three kringle structures. Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth. It displays increased inhibitory activity (ED50 = 70nM) relative to kringles 1-4 (ED50 = 135nM).

Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3. Carrier free (No BSA) form available in stock. If you want this antibody carrier free please specify "Carrier Free" or "No BSA" in your order note.

Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.

Protease Inhibitors, Proteolysis/Ubiquitin, Proteolytic Enzymes

Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.

Boster Bio Anti-Angiostatin K1-3/PLG Antibody catalog # RP1027. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.

Belongs to the peptidase S1 family. Plasminogen subfamily.