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Anti-CD30/TNFRSF8 Antibody Picoband® Europäischer Partner

ArtNr BOS-RP1029
Hersteller Boster
Menge 100 ug/vial
Quantity options 100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Kategorie
Typ Antibody Polyclonal
Format Lyophilized
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Sensitivity <1 pg/ml
Sequence Contains 6 TNFR-Cys repeats.
Citations 1. Fischer, M., Harvima, I. T., Carvalho, R. F. S., Moller, C., Naukkarinen, A., Enblad, G., Nilsson, G. Mast cell CD30 ligand is upregulated in cutaneous inflammation and mediates degranulation-independent chemokine secretion. J. Clin. Invest. 116: 2748-2756, 2006.
2. Gorczyca W, Tsang P, Liu Z, et al. (February 2003). CD30-positive T-cell lymphomas co-expressing CD15: an immunohistochemical analysis. Int. J. Oncol. 22 (2): 319–24.
3. Teng LH, Lu DH, Xu QZ, Fu YJ, Yang H, He ZL (2005). [Expression and diagnostic significance of OCT4, CD117 and CD30 in germ cell tumors]. Zhonghua Bing Li Xue Za Zhi (in Chinese) 34 (11): 711–5.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Tumor necrosis factor receptor superfamily member 8,CD30L receptor,Ki-1 antigen,Lymphocyte activation antigen CD30,CD30,TNFRSF8,CD30,D1S166E
Similar products CD 30 antibody, CD153 antibody, CD30 antibody, CD30 antigen antibody, CD30L receptor antibody, Cytokine receptor CD30 antibody, D1S166E antibody, KI 1 antibody, Ki 1 antigen antibody, Ki-1 antigen antibody, KI1 antibody, Lymphocyte activation antigen CD30 antibody, TNFRSF 8 antibody, TNFRSF8 antibody, TNR8_HUMAN antibody, Tumor Necrosis Factor Receptor Superfamily Member 8 antibody
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Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight
110 kDa
Calculated Molecular weight
63747 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5μg/ml, Human
Gene Name
TNFRSF8
Gene Full Name
Tumor necrosis factor receptor superfamily member 8
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. This gene is mapped to 1p36.22. CD30 is expressed in embryonal carcinoma but not in seminoma and is thus a useful marker in distinguishing between these germ cell tumors. CD30 mast cell activation represents an IgE-independent activation pathway, which is important for understanding cutaneous inflammation associated with mast cells. In addition to those, CD30 is also associated with anaplastic large cell lymphoma.
Immunogen
E.coli-derived human CD30 recombinant protein (Position: T322-K595). Human CD30 shares 60% and 57% amino acid (aa) sequences identity with mouse and rat CD30, respectively.
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category
Cancer, Cell Type Markers, Cytokines, Immunology, Innate Immunity, Receptors, TNF Superfamily, Tumor Biomarkers, Tumor Immunology
Protein Name
Tumor necrosis factor receptor superfamily member 8
Protein Function
Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF- kappa-B.
Subcellular Localization
Isoform 1: Cell membrane; Single-pass type I membrane protein.
Description
Boster Bio Anti-CD30/TNFRSF8 Antibody catalog # RP1029. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Sequence Similarities
Contains 6 TNFR-Cys repeats.
Manufacturer - Cross Reactivity
No cross-reactivity with other proteins

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
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